The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …

This paper is an overview of the applications of microporous membranes for preparation of
micro/nano-emulsions. Membrane emulsification offers compact devices for preparation of …

The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Background The purpose of this study was to screen various drug delivery systems for
improving the aqueous solubility and oral bioavailability of sildenafil. Three representative …

The purpose of this study was to compare two types of emulsification techniques in a solid
self-nanoemulsifying drug delivery system (SNEDDS); high-pressure homogenisation (HPH) …

In this study, a solidified self-nanoemulsifying drug delivery system (solidified SNEDDS) and
surface-modified microspheres were developed for enhancing the oral bioavailability of …

The self-nanoemulsifying drug delivery system has shown many advantages in drug
delivery. In this study, a self-nanoemulsifying drug delivery system of buckwheat flavonoids …

This study aimed to compare high-pressure homogenization (HPH) and Shirasu porous
glass (SPG) membrane emulsification for enhancing the oral bioavailability of rivaroxaban …