Molecular mechanisms of arrhythmogenic cardiomyopathy

KM Austin, MA Trembley, SF Chandler… - Nature Reviews …, 2019 - nature.com
Arrhythmogenic cardiomyopathy is a genetic disorder characterized by the risk of life-
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …

Arrhythmogenic cardiomyopathy: pathology, genetics, and concepts in pathogenesis

ET Hoorntje, WP Te Rijdt, CA James… - Cardiovascular …, 2017 - academic.oup.com
Arrhythmogenic cardiomyopathy (ACM) is a rare, heritable heart disease characterized by
fibro-fatty replacement of the myocardium and a high degree of electric instability. It was first …

Importance of genotype for risk stratification in arrhythmogenic right ventricular cardiomyopathy using the 2019 ARVC risk calculator

A Protonotarios, R Bariani, C Cappelletto… - European heart …, 2022 - academic.oup.com
Aims To study the impact of genotype on the performance of the 2019 risk model for
arrhythmogenic right ventricular cardiomyopathy (ARVC). Methods and results The study …

Sudden death and left ventricular involvement in arrhythmogenic cardiomyopathy

C Miles, G Finocchiaro, M Papadakis, B Gray… - Circulation, 2019 - Am Heart Assoc
Background: Arrhythmogenic cardiomyopathy (ACM) is an inherited heart muscle disorder
characterized by myocardial fibrofatty replacement and an increased risk of sudden cardiac …

The role of genetics in cardiovascular disease: arrhythmogenic cardiomyopathy

CA James, P Syrris, JP Van Tintelen… - European heart …, 2020 - academic.oup.com
Arrhythmogenic cardiomyopathy (ACM) is a heritable cardiomyopathy characterized by
frequent ventricular arrhythmias and progressive ventricular dysfunction. Risk of sudden …

Myocardial inflammation as a manifestation of genetic cardiomyopathies: from bedside to the bench

G Peretto, E Sommariva, C Di Resta, M Rabino… - Biomolecules, 2023 - mdpi.com
Over recent years, preclinical and clinical evidence has implicated myocardial inflammation
(M-Infl) in the pathophysiology and phenotypes of traditionally genetic cardiomyopathies. M …

Arrhythmogenic right ventricular cardiomyopathy: a focused update on diagnosis and risk stratification

LP Bosman, ASJM Te Riele - Heart, 2022 - heart.bmj.com
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy
characterised by fibrofatty replacement of predominantly the right ventricle and high risk of …

State of the art review on genetics and precision medicine in arrhythmogenic cardiomyopathy

V Patel, B Asatryan, B Siripanthong, PB Munroe… - International journal of …, 2020 - mdpi.com
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterised by
ventricular arrhythmia and an increased risk of sudden cardiac death (SCD). Numerous …

Established and emerging mechanisms in the pathogenesis of arrhythmogenic cardiomyopathy: a multifaceted disease

S Gao, D Puthenvedu, R Lombardi… - International journal of …, 2020 - mdpi.com
Arrhythmogenic cardiomyopathy (ACM) is a heritable myocardial disease that manifests with
cardiac arrhythmias, syncope, sudden cardiac death, and heart failure in the advanced …

Arrhythmogenic right ventricular cardiomyopathy

AD Krahn, AAM Wilde, H Calkins, A La Gerche… - Clinical …, 2022 - jacc.org
Arrhythmogenic right ventricular cardiomyopathy (ARVC) encompasses a group of
conditions characterized by right ventricular fibrofatty infiltration, with a predominant …