Impact of gallic acid on gut health: Focus on the gut microbiome, immune response, and mechanisms of action
K Yang, L Zhang, P Liao, Z Xiao, F Zhang… - Frontiers in …, 2020 - frontiersin.org
Gallic acid (GA) is a naturally occurring polyphenol compound present in fruits, vegetables,
and herbal medicines. According to previous studies, GA has many biological properties …
and herbal medicines. According to previous studies, GA has many biological properties …
Gallic acid: A versatile antioxidant with promising therapeutic and industrial applications
Oxidative stress, a result of an overproduction and accumulation of free radicals, is the
leading cause of several degenerative diseases such as cancer, atherosclerosis …
leading cause of several degenerative diseases such as cancer, atherosclerosis …
Multi-step in silico discovery of natural drugs against COVID-19 targeting main protease
In continuation of our antecedent work against COVID-19, three natural compounds, namely,
Luteoside C (130), Kahalalide E (184), and Streptovaricin B (278) were determined as the …
Luteoside C (130), Kahalalide E (184), and Streptovaricin B (278) were determined as the …
Molecular insights into the interaction of RONS and Thieno [3, 2-c] pyran analogs with SIRT6/COX-2: A molecular dynamics study
SIRT6 and COX-2 are oncogenes target that promote the expression of proinflammatory and
pro-survival proteins through a signaling pathway, which leads to increased survival and …
pro-survival proteins through a signaling pathway, which leads to increased survival and …
In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking …
Papain-like protease is an essential enzyme in the proteolytic processing required for the
replication of SARS-CoV-2. Accordingly, such an enzyme is an important target for the …
replication of SARS-CoV-2. Accordingly, such an enzyme is an important target for the …
Spike protein recognizer receptor ACE2 targeted identification of potential natural antiviral drug candidates against SARS-CoV-2
Abstract Angiotensin-converting enzyme 2 (ACE2), also known as peptidyl-dipeptidase A,
belongs to the dipeptidyl carboxydipeptidases family has emerged as a potential antiviral …
belongs to the dipeptidyl carboxydipeptidases family has emerged as a potential antiviral …
Chemo-and bioinformatics resources for in silico drug discovery from medicinal plants beyond their traditional use: a critical review
Covering: up to 2014 In silico approaches have been widely recognised to be useful for drug
discovery. Here, we consider the significance of available databases of medicinal plants and …
discovery. Here, we consider the significance of available databases of medicinal plants and …
Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay
In this study, pharmacophore based 3D QSAR models for human acetylcholinesterase
(AChE) inhibitors were generated, with good significance, statistical values (r2training …
(AChE) inhibitors were generated, with good significance, statistical values (r2training …
A Review of Bioactive Compounds and Antioxidant Activity Properties of Piper Species
Antioxidants are compounds that are able to inhibit the negative effects that come from free
radicals. The phenomenon of imbalanced antioxidant production and the accumulation of …
radicals. The phenomenon of imbalanced antioxidant production and the accumulation of …
Molecular docking, QSAR and ADMET studies of withanolide analogs against breast cancer
Withanolides are a group of pharmacologically active compounds present in most prodigal
amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most …
amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most …