The past few years have brought substantial progress toward understanding how human
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host …

Human cytomegalovirus is a widespread pathogen of major medical importance. It causes
significant morbidity and mortality in immunocompromised individuals, and congenital …

Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

Human cytomegalovirus (HCMV) is a paradigm of pathogen immune evasion and sustains
lifelong persistent infection in the face of exceptionally powerful host immune responses …

Herpesvirus infections are a leading cause of neurodevelopmental delay in newborns and
end-organ disease in immunocompromised patients. One leading strategy to reduce the …

Human cytomegalovirus (HCMV), a ubiquitous beta-herpesvirus, is able to establish lifelong
latency after initial infection. Periodical reactivation occurs after immunosuppression …

Natural killer (NK) cells play an important role in the host response against viral infections
and cancer development. They are able to kill virus-infected and tumor cells, and they …

Human cytomegalovirus is an opportunistic double-stranded DNA virus with one of the
largest viral genomes known. The 235 kB genome is divided in a unique long (UL) and a …