[HTML][HTML] The 5th edition of the World Health Organization classification of haematolymphoid tumours: myeloid and histiocytic/dendritic neoplasms

JD Khoury, E Solary, O Abla, Y Akkari, R Alaggio… - leukemia, 2022 - nature.com
The upcoming 5th edition of the World Health Organization (WHO) Classification of
Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers …

miRNAs as Cornerstones in Chronic Lymphocytic Leukemia Pathogenesis and Therapeutic Resistance–An emphasis on the interaction of signaling pathways

AS Doghish, AI Abulsoud, SS Elshaer… - … -Research and Practice, 2023 - Elsevier
Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia.
Patients of advanced age are more likely to develop the condition, which has a highly varied …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Burkitt lymphoma

C López, B Burkhardt, JKC Chan, L Leoncini… - Nature Reviews …, 2022 - nature.com
Burkitt lymphoma (BL) is an aggressive form of B cell lymphoma that can affect children and
adults. The study of BL led to the identification of the first recurrent chromosomal aberration …

[HTML][HTML] T follicular helper cells in cancer

N Gutiérrez-Melo, D Baumjohann - Trends in cancer, 2023 - cell.com
T follicular helper (Tfh) cells provide essential help to B cells for effective antibody-mediated
immune responses. Although the crucial function of these CD4+ T cells in infection and …

[HTML][HTML] A comparison of the International Consensus and 5th World Health Organization classifications of mature B-cell lymphomas

B Falini, G Martino, S Lazzi - Leukemia, 2023 - nature.com
Several editions of the World Health Organization (WHO) classifications of lympho-
hemopoietic neoplasms in 2001, 2008 and 2017 served as the international standard for …

[HTML][HTML] The WHO classification of haematolymphoid tumours

IA Cree - Leukemia, 2022 - nature.com
The World Health Organization (WHO) Classification of Tumours provides a definitive
classification of all tumours, worldwide. This is essential to underpin the diagnosis and …

Diagnosis and treatment of chronic lymphocytic leukemia: a review

M Shadman - Jama, 2023 - jamanetwork.com
Importance Chronic lymphocytic leukemia (CLL), defined by a minimum of 5× 10 9/L
monoclonal B cells in the blood, affects more than 200 000 people and is associated with …

Implementation of whole-genome and transcriptome sequencing into clinical cancer care

E Cuppen, O Elemento, R Rosenquist, S Nikic… - JCO Precision …, 2022 - ascopubs.org
PURPOSE The combination of whole-genome and transcriptome sequencing (WGTS) is
expected to transform diagnosis and treatment for patients with cancer. WGTS is a …

[HTML][HTML] Artificial intelligence in hematological diagnostics: Game changer or gadget?

W Walter, C Pohlkamp, M Meggendorfer, N Nadarajah… - Blood Reviews, 2023 - Elsevier
The future of clinical diagnosis and treatment of hematologic diseases will inevitably involve
the integration of artificial intelligence (AI)-based systems into routine practice to support the …