Platelets are small non-nucleated cell fragments and the second most abundant cell that
play crucial role in managing vascular integrity and regulating hemostasis. Recent finding …

Direct-acting antiviral drugs (DAAs) are currently replacing antiviral therapy for Hepatitis C
infection. Treatment related side effects are even worse and the emergence of resistant …

Exposure to the dengue virus (DENV) evokes a variety of genetically-controlled
immunological responses. Genetic variants involved in viral entry, replication and innate …

Objectives: Although recent genome-wide association studies have identified a number of
single nucleotide polymorphisms associated with platelet count and mean platelet volume …

Recently, human platelet antigens (HPAs) polymorphisms are found to play a role in
susceptibility to hepatitis C virus (HCV) infection and fibrosis progression. The aim of the …

INTRODUCTION: Hepatic fibrosis progression in patients with chronic hepatitis C virus
infections has been associated with viral and host factors, including genetic polymorphisms …

Hepatitis C virus (HCV) is a major cause of chronic hepatitis. Previous studies have
identified a number of single nucleotide polymorphisms that are associated with HCV …

O ZIKA vírus é um arbovírus da família Flaviviridae e gênero flavivirus, possuindo grandes
semelhanças genéticas e estruturais a outros arbovírus relevantes na área da saúde. A …

Background Host genetic polymorphisms influence the fibrosis progression of chronic
hepatitis C (CHC) patients. Previous studies have shown the association of human platelet …

INTRODUCTION: HPA polymorphism has been associated with HCV presence and fibrosis
progression in chronic hepatitis C. However, it is unknown if there is an association between …