Hypoxia is a common feature of solid tumors, and develops because of the rapid growth of
the tumor that outstrips the oxygen supply, and impaired blood flow due to the formation of …

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival
time of 10-12 months. Clinically, these poor outcomes are attributed to several factors …

Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is
the fourth leading cause of cancer-related deaths in the world. Due to the broad …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic
kidney diseases. Increased apoptosis, epithelial‐to‐mesenchymal transition, and …

Background Pancreatic cancer is associated with an extremely poor prognosis, so new
biomarkers that can detect the initial stages are urgently needed. The significance of serum …

Cutaneous squamous cell carcinoma (cSCC) is the second most common human cancer
with over 250,000 new cases annually in the US and is second in incidence only to basal …

Wnt signaling transduces evolutionarily conserved pathways which play important roles in
initiating and regulating a diverse range of cellular activities, including cell proliferation …

BACKGROUND: MicroRNAs (miRNAs) are a class of small non-coding RNAs regulating
gene expression that play roles in the pathogenesis of human diseases, including …

The identification of small subpopulations of cancer stem cells (CSCs) from blood
mononuclear cells in human acute myeloid leukemia (AML) in 1997 was a landmark …