miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …

Background MicroRNAs have emerged as important regulatory non-coding RNAs that tune
cellular responses to physiological perturbations and disease conditions. An increasing …

Isolation of specific cell types, including pluripotent stem cell (PSC)-derived populations, is
frequently accomplished using cell surface antigens expressed by the cells of interest …

Purpose The unique circulating microRNAs (miRNAs) observed in patients with type 2
diabetes (T2D) are candidates as new biomarkers and therapeutic targets. In order to …

Diabetes, the most common endocrine disorder, also known as a silent killer disease, is
characterized by uncontrolled hyperglycemia. According to the International Diabetes …

MicroRNAs (miRNAs) are noncoding RNAs of~ 22 nucleotides that regulate gene
expression post-transcriptionally by binding to the 3′ untranslated region of messenger …

In the last decade, there has been an explosion in both the number of and knowledge about
miRNAs associated with both type 1 and type 2 diabetes. Even though we are presently in …

Pancreatic differentiation of stem cells will aid treatment of patients with type I diabetes
mellitus (T1DM). Synthetic biopolymers utilization provided extracellular matrix (ECM) and …

Diabetes is one of the most frequently occurring metabolic disorders, affecting almost one
tenth of the global population. Despite advances in antihyperglycemic therapeutics, the …

The bioartificial pancreas (BAP) represents a viable solution for the treatment of type 1
diabetes (T1D). By encapsulating pancreatic cells in a semipermeable membrane to allow …