Derivation of human primordial germ cell-like cells in an embryonic-like culture
SN Esfahani, Y Zheng, A Arabpour, AMR Irizarry… - Nature …, 2024 - nature.com
Primordial germ cells (PGCs) are the embryonic precursors of sperm and eggs. They
transmit genetic and epigenetic information across generations. Given the prominent role of …
transmit genetic and epigenetic information across generations. Given the prominent role of …
In Vitro gametogenesis in oncofertility: a review of its potential use and present-day challenges in moving toward fertility preservation and restoration
VG Wesevich, C Arkfeld, DB Seifer - Journal of Clinical Medicine, 2023 - mdpi.com
Current fertility preservation options are limited for cancer survivor patients who wish to have
their own biological children. Human in vitro gametogenesis (IVG) has the hypothetical …
their own biological children. Human in vitro gametogenesis (IVG) has the hypothetical …
Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation
X-chromosome dosage compensation in female placental mammals is achieved by X-
chromosome inactivation (XCI). Human pre-implantation embryos are an exception, in which …
chromosome inactivation (XCI). Human pre-implantation embryos are an exception, in which …
In vitro germ cell induction from fertile and infertile monozygotic twin research participants
Human induced pluripotent stem cells (hiPSCs) enable reproductive diseases to be studied
when the reproductive health of the participant is known. In this study, monozygotic (MZ) …
when the reproductive health of the participant is known. In this study, monozygotic (MZ) …
In Vitro Maturation, In Vitro Oogenesis, and Ovarian Longevity
SJ Silber, S Goldsmith, L Castleman, K Hayashi - Reproductive Sciences, 2024 - Springer
This paper will review a remarkable new approach to in vitro maturation “IVM” of oocytes
from ovarian tissue, based on our results with in vitro oogenesis from somatic cells. As an …
from ovarian tissue, based on our results with in vitro oogenesis from somatic cells. As an …
[HTML][HTML] Generation of six human induced pluripotent stem cell sublines (MZT01E, MZT01F, MZT01N and MZT02D, MZT02G and MZT02H) for reproductive science …
Six human induced pluripotent stem cell sublines (hiPSCs) were generated from human
dermal fibroblasts (HDFs) derived from skin biopsies donated from monozygotic twin women …
dermal fibroblasts (HDFs) derived from skin biopsies donated from monozygotic twin women …
[HTML][HTML] Generation of three human induced pluripotent stem cell sublines (UCLAi005-A, UCLAi005-B and UCLAi005-C) for reproductive science research
We generated three human induced pluripotent stem cell (hiPSC) sublines from human
dermal fibroblasts (HDF)(MZT05) generated from a skin biopsy donated from a previously …
dermal fibroblasts (HDF)(MZT05) generated from a skin biopsy donated from a previously …
[HTML][HTML] Generation of three human induced pluripotent stem cell sublines (UCLAi004-A, UCLAi004-B, and UCLAi004-C) for reproductive science research
EC Pandolfi, TJ Hunt, S Goldsmith, K Hurlbut, SJ Silber… - Stem cell …, 2021 - Elsevier
Three induced pluripotent stem cell sublines (hiPSCs) were generated from human dermal
human dermal fibroblasts (HDFs) derived from a human skin punch biopsy. The biopsy was …
human dermal fibroblasts (HDFs) derived from a human skin punch biopsy. The biopsy was …