Curcumin and cancer

A Giordano, G Tommonaro - Nutrients, 2019 - mdpi.com
Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

The role of curcumin in cancer treatment

V Zoi, V Galani, GD Lianos, S Voulgaris, AP Kyritsis… - Biomedicines, 2021 - mdpi.com
Curcumin is a polyphenol extracted from the rhizomes of the turmeric plant, Curcuma longa
which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated …

[HTML][HTML] Exploring the multifocal role of phytochemicals as immunomodulators

T Behl, K Kumar, C Brisc, M Rus… - Biomedicine & …, 2021 - Elsevier
A well-functioning immune system of the host body plays pivotal role in the maintenance of
ordinary physiological and immunological functions as well as internal environment …

Structural insights into three sesquiterpene synthases for the biosynthesis of tricyclic sesquiterpenes and chemical space expansion by structure-based mutagenesis

T Lou, A Li, H Xu, J Pan, B Xing, R Wu… - Journal of the …, 2023 - ACS Publications
The cyclization of farnesyl diphosphate (FPP) into highly strained polycyclic sesquiterpenes
is challenging. We here determined the crystal structures of three sesquiterpene synthases …

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways

J Dai, L Gu, Y Su, Q Wang, Y Zhao, X Chen… - International …, 2018 - Elsevier
Abstract Oxidative stress, Nrf2-HO-1 and TLR-MAPK/NF-κB signaling pathways have been
proved to be involved in influenza A virus (IAV) replication and influenzal pneumonia. In the …

Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways

I Jantan, MA Haque, L Arshad, H Harikrishnan… - The Journal of nutritional …, 2021 - Elsevier
The high failure rate of the reductionist approach to discover effective and safe drugs to treat
chronic inflammatory diseases has led scientists to seek alternative ways. Recently …

Exploring the Leaves of Annona muricata L. as a Source of Potential Anti-inflammatory and Anticancer Agents

SM Abdul Wahab, I Jantan, MA Haque… - Frontiers in …, 2018 - frontiersin.org
The use of anti-inflammatory natural products to treat inflammatory disorders for cancer
prevention and therapy is an appealing area of interest in the last decades. Annona …

[HTML][HTML] Targeted therapies of curcumin focus on its therapeutic benefits in cancers and human health: Molecular signaling pathway-based approaches and future …

MR Islam, A Rauf, S Akash, SI Trisha, AH Nasim… - Biomedicine & …, 2024 - Elsevier
The curry powder spices turmeric (Curcuma longa L.), which contains curcumin
(diferuloylmethane), an orange-yellow chemical. Polyphenols are the most commonly used …

Immunomodulatory properties of triterpenes

G Renda, İ Gökkaya, D Şöhretoğlu - Phytochemistry Reviews, 2022 - Springer
The immune system is one of the main defence mechanisms of the human body.
Inadequacy of this system or immunodeficiency results in increased risk of infections and …

An Insight Into the Modulatory Effects and Mechanisms of Action of Phyllanthus Species and Their Bioactive Metabolites on the Immune System

I Jantan, MA Haque, M Ilangkovan… - Frontiers in …, 2019 - frontiersin.org
Phyllanthus species (family; Euphorbiaceae) have been intensively studied for their
immunomodulating effects due to their wide-ranging uses to treat immune-related diseases …