Isotype switching in human memory B cells sets intrinsic antigen-affinity thresholds that...

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B cell receptor silencing reveals the origin of high-grade B cell lymphomas with MYC and BCL2 rearrangements

P Sindaco, S Lonardi, G Varano, I Pietrini, G Morello… - bioRxiv, 2024 - biorxiv.org
The B cell receptor (BCR) is essential for mature B cell lymphomas, serving as therapeutic
target. Here, we show that high-grade B cell lymphomas with MYC and BCL2 …
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