Glioblastoma (GBM) is an aggressive central nervous system cancer with a dismal
prognosis. The standard of care involves surgical resection followed by radiotherapy and …

Glioblastoma (GBM), a highly lethal brain tumor, has been comprehensively characterized at
the molecular level with the identification of several potential treatment targets. Data …

Simple Summary Intratumoral heterogeneity is believed to contribute to the immense
therapy resistance and recurrence rate of glioblastoma. The aim of this retrospective study …

The concept of the Myc (c-myc, n-myc, l-myc) oncogene as a canonical, DNA-bound
transcription factor has consistently changed over the past few years. Indeed, Myc controls …

In this study we assessed whether gliomas could be subdivided into different molecular
subtypes by immunohistochemistry (IHC) reminiscent of those first described by Verhaak et …

Purpose: Molecular subtype classifications in glioblastoma may detect therapy sensitivities.
IHC would potentially allow the identification of molecular subtypes in routine clinical …

Purpose Glioblastoma is the most aggressive form of brain tumors. A better understanding of
the molecular mechanisms leading to its evolution is essential for the development of …

Glioblastoma (GBM) is the most frequent primary malignant brain tumor and has a dismal
prognosis. Unfortunately, despite the recent revolution of immune checkpoint inhibitors in …

Glioblastoma is one of the deadliest tumors with barely over one-year median survival
despite intensive efforts in defining its molecular characteristics and searching for innovative …

Background: Glioblastoma multiforme (GBM) is the most aggressive brain tumor that occurs
in adults. In spite of prompt diagnosis and rapidly administered treatment, the survival …