The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and
small intestine, comprised of ulcerative colitis and Crohn's disease. Among the complicated …

The endocannabinoid system is represented by a group of neuromodulatory lipids and their
receptors that are involved in a variety of physiological and pathological conditions. The …

Endocannabinoids are host-derived lipid hormones that fundamentally impact
gastrointestinal (GI) biology. The use of cannabis and other exocannabinoids as anecdotal …

Background Clinical trials investigating the use of cannabinoid drugs for the treatment of
intestinal inflammation are anticipated secondary to preclinical literature demonstrating …

Cannabis sativa and its extracts have been used for centuries, both medicinally and
recreationally. There is accumulating evidence that exogenous cannabis and related …

The cannabinoid receptor subtype 2 (CB2R) represents an interesting and new therapeutic
target for its involvement in the first steps of neurodegeneration as well as in cancer onset …

Intestinal mucosal barrier, mainly composed of the intestinal mucus layer and the epithelium,
plays a critical role in nutrient absorption as well as protection from pathogenic …

Decades of research has provided evidence for the role of the endocannabinoid system in
human health and disease. This versatile system, consisting of two receptors (CB1 and …