Discovery, synthesis, and structure–activity relationships of conotoxins
Peptide therapeutics are acclaimed as a promising addition to the pharmaceutical arena,
and they continue to attract interest due to their high potency, bioavailability, and fewer …
and they continue to attract interest due to their high potency, bioavailability, and fewer …
Cysteine‐Rich Antifungal Proteins from Filamentous Fungi are Promising Bioactive Natural Compounds in Anti‐Candida Therapy
L Galgóczy, A Yap, F Marx - Israel Journal of Chemistry, 2019 - Wiley Online Library
The emerging number of life‐threatening invasive fungal infections caused by drug‐resistant
Candida strains urges the need for the development and application of fundamentally new …
Candida strains urges the need for the development and application of fundamentally new …
Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ-conotoxin KIIIA disulfide isomers
μ-Conotoxins are components of cone snail venom, well-known for their analgesic activity
through potent inhibition of voltage-gated sodium channel (Na V) subtypes, including Na V …
through potent inhibition of voltage-gated sodium channel (Na V) subtypes, including Na V …
Total synthesis of human hepcidin through regioselective disulfide‐bond formation by using the safety‐catch cysteine protecting group 4, 4 …
A safety‐catch cysteine protecting group, S‐4, 4′‐dimethylsulfinylbenzhydryl (Msbh), was
designed and developed to expand the capabilities of synthetic strategies for the …
designed and developed to expand the capabilities of synthetic strategies for the …
Conformational μ-conotoxin PIIIA isomers revisited: Impact of cysteine pairing on disulfide-bond assignment and structure elucidation
P Heimer, AA Tietze, CA Bäuml… - Analytical …, 2018 - ACS Publications
Peptides and proteins carrying high numbers of cysteines can adopt various 3D structures
depending on their disulfide connectivities. The unambiguous verification of such …
depending on their disulfide connectivities. The unambiguous verification of such …
Racemisation of N‐Fmoc phenylglycine under mild microwave‐SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this
We have been engaged in the microwave‐solid phase peptide synthesis (SPPS) synthesis
of the phenylglycine (Phg)‐containing pentapeptide H‐Ala‐Val‐Pro‐Phg‐Tyr‐NH2 (1) …
of the phenylglycine (Phg)‐containing pentapeptide H‐Ala‐Val‐Pro‐Phg‐Tyr‐NH2 (1) …
Synthesis of PAF, an Antifungal Protein from P. chrysogenum, by Native Chemical Ligation: Native Disulfide Pattern and Fold Obtained upon Oxidative Refolding
G Váradi, GK Tóth, Z Kele, L Galgóczy… - … A European Journal, 2013 - Wiley Online Library
The folding of disulfide proteins is of considerable interest because knowledge of this may
influence our present understanding of protein folding. However, sometimes even the …
influence our present understanding of protein folding. However, sometimes even the …
Synthetic strategies for macrocyclic peptides
É Biron, S Vézina‐Dawod… - … Medicinal Chemistry with …, 2017 - Wiley Online Library
Peptide macrocycles form an outstanding class of natural and synthetic bioactive
compounds. This chapter discusses synthetic strategies for the final ring‐closing reaction by …
compounds. This chapter discusses synthetic strategies for the final ring‐closing reaction by …
Blood analysis by Raman spectroscopy for laser stimulation on mouse prefrontal cortex
SY Li, YD Xia, J Tian, C Shan, H Zhang… - Brain Network and …, 2022 - journals.lww.com
Low-level laser therapy, a noninvasive physical therapy, is applied to a wide range of
conditions and has many effects including anti-inflammatory, analgesic, and anti-allergic …
conditions and has many effects including anti-inflammatory, analgesic, and anti-allergic …
A Comparative Examination of two Fmoc Removal Reagents for Process Improvement to Produce Peptide Drugs
K Srivastava - Peptides for Youth: The Proceedings of the 20th …, 2009 - Springer
The importance of peptides as therapeutics has been recognized since they were found
responsible for a wide variety of biological functions. The recent approval of peptide drugs …
responsible for a wide variety of biological functions. The recent approval of peptide drugs …