Laser speckle contrast imaging: theoretical and practical limitations

D Briers, DD Duncan, E Hirst… - … of biomedical optics, 2013 - spiedigitallibrary.org
When laser light illuminates a diffuse object, it produces a random interference effect known
as a speckle pattern. If there is movement in the object, the speckles fluctuate in intensity …

Laser speckle imaging to monitor microvascular blood flow: a review

PG Vaz, A Humeau-Heurtier, E Figueiras… - IEEE reviews in …, 2016 - ieeexplore.ieee.org
Laser speckle is a complex interference phenomenon that can easily be understood, in
concept, but is difficult to predict mathematically, because it is a stochastic process. The use …

Expanding applications, accuracy, and interpretation of laser speckle contrast imaging of cerebral blood flow

SMS Kazmi, LM Richards, CJ Schrandt… - Journal of Cerebral …, 2015 - journals.sagepub.com
Laser speckle contrast imaging (LSCI) provides a rapid characterization of cortical flow
dynamics for functional monitoring of the microcirculation. The technique stems from …

Flux or speed? Examining speckle contrast imaging of vascular flows

SMS Kazmi, E Faraji, MA Davis, YY Huang… - Biomedical optics …, 2015 - opg.optica.org
Speckle contrast imaging enables rapid mapping of relative blood flow distributions using
camera detection of back-scattered laser light. However, speckle derived flow measures …

Hypothermia-induced neuroprotection is associated with reduced mitochondrial membrane permeability in a swine model of cardiac arrest

P Gong, R Hua, Y Zhang, H Zhao… - Journal of Cerebral …, 2013 - journals.sagepub.com
Increasing evidence has shown that mild hypothermia is neuroprotective for comatose
patients resuscitated from cardiac arrest, but the mechanism of this protection is not fully …

Chronic imaging of cortical blood flow using Multi-Exposure Speckle Imaging

SMS Kazmi, AB Parthasarthy… - Journal of Cerebral …, 2013 - journals.sagepub.com
Chronic imaging of cerebral blood flow (CBF) is an important tool for investigating vascular
remodeling after injury such as stroke. Although techniques such as Laser Speckle Contrast …

Spreading depolarization remarkably exacerbates ischemia-induced tissue acidosis in the young and aged rat brain

Á Menyhárt, D Zölei-Szénási, T Puskás, P Makra… - Scientific reports, 2017 - nature.com
Spreading depolarizations (SDs) occur spontaneously in the cerebral cortex of
subarachnoid hemorrhage, stroke or traumatic brain injury patients. Accumulating evidence …

Optimization of camera exposure durations for multi-exposure speckle imaging of the microcirculation

SMS Kazmi, S Balial, AK Dunn - Biomedical optics express, 2014 - opg.optica.org
Improved Laser Speckle Contrast Imaging (LSCI) blood flow analyses that incorporate
inverse models of the underlying laser-tissue interaction have been used to develop more …

Molecular hydrogen affords neuroprotection in a new translational piglet model of hypoxic-ischemic encephalopathy

J Németh - 2017 - search.proquest.com
Perinatal asphyxia (PA) is one of the leading causes of neonatal mortality and morbidity
worldwide. Despite the adequate neonatal resuscitation techniques, hypoxicischemic …

Histogram analysis of laser speckle contrast image for cerebral blood flow monitoring

AS Abdurashitov, VV Lychagov, OA Sindeeva… - Frontiers of …, 2015 - Springer
Laser speckle contrast imaging (LSCI) is a powerful tool for blood flow mapping. In this
paper, we described a simple algorithm based on histogram analysis of laser speckle …