T follicular helper (Tfh) cells provide essential help to B cells for effective antibody-mediated
immune responses. Although the crucial function of these CD4+ T cells in infection and …

Germinal centres (GC) are lymphoid structures in which B cells acquire affinity-enhancing
somatic hypermutations (SHM), with surviving clones differentiating into memory B cells …

With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Follicular lymphoma, the most common indolent lymphoma, though highly responsive to
therapy is coupled with multiple relapses for the majority of patients. Advances in biologic …

Follicular lymphoma (FL) is a B-cell malignancy with a complex tumor microenvironment that
is rich in nonmalignant immune cells. We applied single-cell RNA sequencing to …

The primary two-dose SARS-CoV-2 mRNA vaccine series are strongly immunogenic in
humans, but the emergence of highly infectious variants necessitated additional doses and …

The redirection of T cells has emerged as an attractive therapeutic principle in B cell non-
Hodgkin lymphoma (B-NHL). However, a detailed characterization of lymphoma-infiltrating T …

The variable clinical course of follicular lymphoma (FL) is determined by the molecular
heterogeneity of tumor cells and complex interactions within the tumor microenvironment …

The use of functional quantitative biomarkers extracted from routine PET–CT scans to
characterize clinical responses in patients with lymphoma is gaining increased attention …

Follicular lymphoma (FL) is a generally incurable malignancy that evolves from
developmentally blocked germinal center (GC) B cells. To promote survival and immune …