Chitosan-based nanomaterials have attracted significant attention in the biomedical field
because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature …

In the last two decades, numerous in vitro studies demonstrated that insulin receptors and
theirs downstream pathways are widely distributed throughout the brain. This evidence has …

There is growing evidence that patients with Type 2 diabetes have an increased risk of
developing Parkinson's disease and share similar dysregulated pathways suggesting …

Highlights•GLP-1 analogs can cross the blood–brain barrier and stimulate the GLP-1
receptor in the brain.•Stimulation of the GLP-1 receptor has shown effects on mitochondrial …

Alzheimer disease (AD) is the most common form of dementia among the elderly and is
characterized by progressive loss of memory and cognition. Epidemiological data show that …

Alzheimer's disease (AD) is the sixth leading cause of death in the USA today; therefore, it is
imperative that public health initiatives and clinical strategies are developed to prevent and …

A growing body of evidence links type-2 diabetes (T2D) with dementia and
neurodegenerative diseases such as Alzheimer's disease (AD). AD is the most common …

Despite intensive research efforts over the past few decades, the mechanisms underlying
the etiology of sporadic Alzheimer's disease (AD) remain unknown. This fact is of major …

Introduction: The effects of sodium-glucose cotransporter 2 inhibitors (SGLT2I) and
dipeptidyl peptidase-4 inhibitors (DPP4I) on new-onset cognitive dysfunction in type 2 …

Type 2 diabetes (T2D) is associated with multiple comorbidities, including diabetic
retinopathy (DR) and cognitive decline, and T2D patients have a significantly higher risk of …