Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Abstract The PRoteomics IDEntifications (PRIDE) database (https://www. ebi. ac. uk/pride/) is
the world's largest data repository of mass spectrometry-based proteomics data, and is one …

Proteogenomics refers to the integrated analysis of the genome and proteome that
leverages mass-spectrometry (MS)-based proteomics data to improve genome annotations …

Human disease phenotypes are driven primarily by alterations in protein expression and/or
function. To date, relatively little is known about the variability of the human proteome in …

Understanding the relationship between genotypes and phenotypes is essential to
disentangle biological mechanisms and to unravel the molecular basis of diseases. Genes …

Multiple types of molecular data for the same set of clinical samples are increasingly
available and may be analyzed jointly in an integrative analysis to maximize comprehensive …

Genomic diversity plays critical roles in risk of disease pathogenesis and diagnosis. While
genomic variants—including single nucleotide variants, frameshift variants, and mis-splicing …

Background: Due to its ability to provide quantitative and dynamic information on tumor
genesis and development by directly profiling protein expression, the proteomics has …

Proteogenomics refers to the integration of high-throughput genomics/transcriptomics with
proteomics data for genome annotation, novel gene discovery, and variant peptide detection …

Cross-talk between genes, transcripts, and proteins is the key to cellular responses; hence,
analysis of molecular levels as distinct entities is slowly being extended to integrative …