Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive
impairments in patients with neurodegenerative disorders. To understand the contribution of …

Adult hippocampal neurogenesis (AHN) facilitates hippocampal circuits plasticity and
regulates hippocampus‐dependent cognition and emotion. However, AHN malfunction has …

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease that
leads to the death of motor and cortical neurons. The clinical manifestations of ALS are …

Alzheimer´ s disease (AD), the most common form of dementia in industrialized countries,
severely targets the hippocampal formation in humans and mouse models of this condition …

Adult hippocampal neurogenesis is critical for learning and memory, and aberrant adult
neurogenesis has been implicated in cognitive decline associated with aging and …

Optical imaging of calcium signals in the brain has enabled researchers to observe the
activity of hundreds-to-thousands of individual neurons simultaneously. Current methods …

Adult hippocampal neurogenesis (AHN) has been widely confirmed in mammalian brains. A
growing body of evidence points to the fact that AHN sustains hippocampal-dependent …

The mammalian hippocampus can generate new neurons throughout life. Known as adult
hippocampal neurogenesis (AHN), this process participates in learning, memory, mood …

Abstract Vacuolar protein sorting 35 (VPS35), a critical component of the retromer complex,
plays a pivotal role in the pathogenesis of neurodegenerative diseases (NDs). It is involved …

Adult hippocampal neurogenesis enhances brain plasticity and contributes to the cognitive
reserve during aging. Adult hippocampal neurogenesis is impaired in neurological …