Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

[HTML][HTML] Spatial single cell metabolomics: current challenges and future developments

KDG Saunders, HM Lewis, DJV Beste, O Cexus… - Current opinion in …, 2023 - Elsevier
Single cell metabolomics is a rapidly advancing field of bio-analytical chemistry which aims
to observe cellular biology with the greatest detail possible. Mass spectrometry imaging and …

An integrated analysis and comparison of serum, saliva and sebum for COVID-19 metabolomics

M Spick, HM Lewis, CF Frampas, K Longman… - Scientific reports, 2022 - nature.com
The majority of metabolomics studies to date have utilised blood serum or plasma, biofluids
that do not necessarily address the full range of patient pathologies. Here, correlations …

No skin off your back: the sampling and extraction of sebum for metabolomics

C Géhin, J Tokarska, SJ Fowler, PE Barran, DK Trivedi - Metabolomics, 2023 - Springer
Introduction Sebum-based metabolomics (a subset of “sebomics”) is a developing field that
involves the sampling, identification, and quantification of metabolites found in human …

[HTML][HTML] Untargeted saliva metabolomics by liquid chromatography—Mass spectrometry reveals markers of COVID-19 severity

CF Frampas, K Longman, M Spick, HM Lewis… - PLoS …, 2022 - journals.plos.org
Background The COVID-19 pandemic is likely to represent an ongoing global health issue
given the potential for new variants, vaccine escape and the low likelihood of eliminating all …

Meta-analysis of COVID-19 metabolomics identifies variations in robustness of biomarkers

A Onoja, J Von Gerichten, HM Lewis, MJ Bailey… - International journal of …, 2023 - mdpi.com
The global COVID-19 pandemic resulted in widespread harms but also rapid advances in
vaccine development, diagnostic testing, and treatment. As the disease moves to endemic …

[HTML][HTML] Systematic review with meta-analysis of diagnostic test accuracy for COVID-19 by mass spectrometry

M Spick, HM Lewis, MJ Wilde, C Hopley, J Huggett… - Metabolism, 2022 - Elsevier
Background The global COVID-19 pandemic has led to extensive development in many
fields, including the diagnosis of COVID-19 infection by mass spectrometry. The aim of this …

[HTML][HTML] Does mask wearing affect skin health? An untargeted skin metabolomics study

Y Liu, H Zhao, H Chen, X Li, C Ran, H Sun… - Environment …, 2023 - Elsevier
Wearing masks is used as an effective way to prevent the spread of viruses. However, the
effect of wearing masks on skin health requires further assessment. In this study, a non …

Epidermal Secretion-purified Biosensing Patch with Hydrogel Sebum Filtering Membrane and Unidirectional Flow Microfluidic Channels

Y Wang, Z Zhang, Y Shi, X Yu, X Zhang, X Ma, J Su… - Biomaterials, 2024 - Elsevier
The development of biosensing electronics for real-time sweat analysis has attracted
increasing research interest due to their promising applications for non-invasive health …

Noninvasive diagnostic for COVID-19 from saliva biofluid via FTIR spectroscopy and multivariate analysis

MHC Nascimento, WD Marcarini, GS Folli… - Analytical …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the worst
global health crisis in living memory. The reverse transcription polymerase chain reaction …