Decellularized extracellular matrix for remodeling bioengineering organoid's microenvironment

L Zhu, J Yuhan, H Yu, B Zhang, K Huang, L Zhu - Small, 2023 - Wiley Online Library
Over the past decade, stem cell‐and tumor‐derived organoids are the most promising
models in developmental biology and disease modeling, respectively. The matrix is one of …

[HTML][HTML] Functional acellular matrix for tissue repair

B Wang, T Qinglai, Q Yang, M Li, S Zeng, X Yang… - Materials Today Bio, 2023 - Elsevier
In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

Challenges with the development of biomaterials for sustainable tissue engineering

DF Williams - Frontiers in bioengineering and biotechnology, 2019 - frontiersin.org
The field of tissue engineering has tantalizingly offered the possibility of regenerating new
tissue in order to treat a multitude of diseases and conditions within the human body …

Strategies based on organ decellularization and recellularization

KH Hillebrandt, H Everwien, N Haep… - Transplant …, 2019 - Wiley Online Library
Transplantation is the only curative treatment option available for patients suffering from end‐
stage organ failure, improving their quality of life and long‐term survival. However, because …

Cell-seeded biomaterial scaffolds: the urgent need for unanswered accelerated angiogenesis

H Shokrani, A Shokrani, SM Sajadi, F Seidi… - International journal …, 2022 - Taylor & Francis
One of the most arduous challenges in tissue engineering is neovascularization, without
which there is a lack of nutrients delivered to a target tissue. Angiogenesis should be …

Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

L Urbani, C Camilli, DE Phylactopoulos… - Nature …, 2018 - nature.com
A tissue engineered oesophagus could overcome limitations associated with oesophageal
substitution. Combining decellularized scaffolds with patient-derived cells shows promise for …

Bioengineering human intestinal mucosal grafts using patient-derived organoids, fibroblasts and scaffolds

L Meran, L Tullie, S Eaton, P De Coppi, VSW Li - Nature Protocols, 2023 - nature.com
Tissue engineering is an interdisciplinary field that combines stem cells and matrices to form
functional constructs that can be used to repair damaged tissues or regenerate whole …

Human-scale lung regeneration based on decellularized matrix scaffolds as a biologic platform

K Ohata, HC Ott - Surgery today, 2020 - Springer
Lung transplantation is currently the only curative treatment for patients with end-stage lung
disease; however, donor organ shortage and the need for intense immunosuppression limit …

Acellular human lung scaffolds to model lung disease and tissue regeneration

SE Gilpin, DE Wagner - European Respiratory Review, 2018 - Eur Respiratory Soc
Recent advances in whole lung bioengineering have opened new doors for studying lung
repair and regeneration ex vivo using acellular human derived lung tissue scaffolds …

Regenerative medicine: postnatal approaches

PKH Tam, KKY Wong, A Atala, GG Giobbe… - The Lancet Child & …, 2022 - thelancet.com
Paper 2 of the paediatric regenerative medicine Series focuses on recent advances in
postnatal approaches. New gene, cell, and niche-based technologies and their …