Synthesis, biomedical applications, and toxicity of CuO nanoparticles

S Naz, A Gul, M Zia, R Javed - Applied Microbiology and Biotechnology, 2023 - Springer
Versatile nature of copper oxide nanoparticles (CuO NPs) has made them an imperative
nanomaterial being employed in nanomedicine. Various physical, chemical, and biological …

Cu-related agents for cancer therapies

C Wang, X Yang, C Dong, K Chai, J Ruan… - Coordination Chemistry …, 2023 - Elsevier
As an indispensable micronutrient, copper (Cu) plays an important role in promoting
metabolism and maintaining various basic biological functions. Copper homeostasis in the …

Biogenic copper oxide nanoparticles from Bacillus coagulans induced reactive oxygen species generation and apoptotic and anti-metastatic activities in breast …

M Dolati, F Tafvizi, M Salehipour, T Komeili Movahed… - Scientific Reports, 2023 - nature.com
The present study examined the anticancer capabilities of Bacillus coagulans supernatant-
produced copper oxide nanoparticles (BC-CuONPs) on MCF-7 and SKBR3 cancer cells …

Subcutaneous Rapid Dissolution Microneedle Patch Integrated with CuO2 and Disulfiram for Augmented Antimelanoma Efficacy through Multimodal Synergy of …

S Yu, H Ni, X Xu, Y Cai, J Feng… - ACS Biomaterials Science …, 2023 - ACS Publications
Melanoma is a malignancy of the skin that is resistant to conventional treatment,
necessitating the development of effective and safe new therapies. The percutaneous …

Metallic nanoparticles for the modulation of tumor microenvironment; a new horizon

S Shariatzadeh, N Moghimi, F Khalafi… - … in Bioengineering and …, 2022 - frontiersin.org
Cancer is one of the most critical human challenges which endangers many people's lives
every year with enormous direct and indirect costs worldwide. Unfortunately, despite many …

Fabrication, characterization and in vitro evaluation of disulfiram-loaded cellulose acetate/poly (ethylene oxide) nanofiber scaffold for breast and colon cancer cell …

G El Fawal, MM Abu-Serie, H El-Gendi… - International Journal of …, 2022 - Elsevier
Cancer and microbial infections threaten human health. Currently, chemotherapeutic drugs
for cancer lack selectivity between normal and cancer cells, exacerbating this problem …

Anti-metastatic breast cancer potential of novel nanocomplexes of diethyldithiocarbamate and green chemically synthesized iron oxide nanoparticles

MM Abu-Serie, EZA Abdelfattah - International Journal of Pharmaceutics, 2022 - Elsevier
Mortality rate of metastatic breast cancer is linked to cancer stem cells (CSCs)'aggressive
features (chemoresistance to apoptosis and redox imbalance). Therefore, unique dual …

Biofabrication of ecofriendly copper oxide nanoparticles and their applications in breast cancer therapy

AP Roy, S Mitra, S Sarkar, R Sahu, G Nandi… - Inorganic Chemistry …, 2024 - Elsevier
Metal oxide nanoparticles are gaining close attention in recent years due to their varied
physicochemical characteristics and applications in various fields, particularly nanomedicine …

Preparation of poly (vinyl alcohol) nanofibers containing disulfiram-copper complex by electrospinning: A potential delivery system against melanoma

GF El Fawal, MM Abu-Serie - DARU Journal of Pharmaceutical Sciences, 2024 - Springer
Background Melanoma poses a significant threat to human health, making the development
of a safe and effective treatment a crucial challenge. Disulfiram (DS) is a proven anticancer …

Targeted ferroptotic potency of ferrous oxide nanoparticles-diethyldithiocarbamate nanocomplex on the metastatic liver cancer

MM Abu-Serie - Frontiers in Pharmacology, 2023 - frontiersin.org
Existing treatments are frequently ineffective in combating liver cancer (LC) due to its rapid
growth, high metastatic potential, and chemoresistance. Thus, inducing ferroptosis, a new …