Tumor microenvironment in gastric cancers
Y Oya, Y Hayakawa, K Koike - Cancer science, 2020 - Wiley Online Library
The tumor microenvironment favors the growth and expansion of cancer cells. Many cell
types are involved in the tumor microenvironment such as inflammatory cells, fibroblasts …
types are involved in the tumor microenvironment such as inflammatory cells, fibroblasts …
Macrophage targeting: opening new possibilities for cancer immunotherapy
L Cassetta, T Kitamura - Immunology, 2018 - Wiley Online Library
Tumour‐infiltrating immune cells regulate tumour development and progression either
negatively or positively. For example, cytotoxic lymphocytes (CTL) such as CD8+ T and …
negatively or positively. For example, cytotoxic lymphocytes (CTL) such as CD8+ T and …
Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence
JY Liu, GP Souroullas, BO Diekman… - Proceedings of the …, 2019 - National Acad Sciences
The activation of cellular senescence throughout the lifespan promotes tumor suppression,
whereas the persistence of senescent cells contributes to aspects of aging. This theory has …
whereas the persistence of senescent cells contributes to aspects of aging. This theory has …
[HTML][HTML] Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target
Macrophages play crucial roles in protecting our bodies from infection and cancers. As
macrophages are multi-functional immune cells, they have diverse plastic subsets, such as …
macrophages are multi-functional immune cells, they have diverse plastic subsets, such as …
Platelet‐rich fibrin elicits an anti‐inflammatory response in macrophages in vitro
Background Platelet‐rich fibrin (PRF) serves as a reservoir of bioactive molecules to support
wound healing and bone regeneration. The beneficial action of PRF might involve …
wound healing and bone regeneration. The beneficial action of PRF might involve …
Helicobacter pylori infection induces stem cell-like properties in Correa cascade of gastric cancer
JJ He, WC Hu, Q Ouyang, SW Zhang, LJ He, WY Chen… - Cancer Letters, 2022 - Elsevier
Gastric cancer (GC) is the fourth leading cause of cancer-related death. Its poor prognosis is
attributed to unclear pathogenesis. Currently, the most widely accepted model for …
attributed to unclear pathogenesis. Currently, the most widely accepted model for …
Macrophage phenotypic mechanomodulation of enhancing bone regeneration by superparamagnetic scaffold upon magnetization
S Hao, J Meng, Y Zhang, J Liu, X Nie, F Wu, Y Yang… - Biomaterials, 2017 - Elsevier
Macrophages are involved in all phases of scaffold induced tissue regeneration,
orchestrating the transition from an inflammatory to regenerative phenotype to guide all …
orchestrating the transition from an inflammatory to regenerative phenotype to guide all …
[HTML][HTML] Tendon immune regeneration: insights on the synergetic role of stem and immune cells during tendon regeneration
V Russo, M El Khatib, G Prencipe, MR Citeroni… - Cells, 2022 - mdpi.com
Tendon disorders represent a very common pathology in today's population, and
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …
Trophoblast-secreted soluble-PD-L1 modulates macrophage polarization and function
Decidual macrophages are in close contact with trophoblast cells during placenta
development, and an appropriate crosstalk between these cellular compartments is crucial …
development, and an appropriate crosstalk between these cellular compartments is crucial …
[HTML][HTML] Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment
CG Cess, SD Finley - PLoS computational biology, 2020 - journals.plos.org
Within the tumor microenvironment, macrophages exist in an immunosuppressive state,
preventing T cells from eliminating the tumor. Due to this, research is focusing on …
preventing T cells from eliminating the tumor. Due to this, research is focusing on …