Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Fibrosis contributes to~ 45% of deaths in western countries. In chronic liver disease, fibrosis
is a major factor determining outcomes, but efficient antifibrotic therapies are lacking …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

Abstract Professor Geoffrey Burnstock proposed the concept of purinergic signaling via P1
and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …

The cloning of a human G-protein-coupled receptor (GPCR) that specifically responds to
UDP-glucose and related sugar-nucleotides has been reported recently. This receptor has …

The current status of ligand gated ion channel P2X and G protein-coupled P2Y receptor
subtypes is described. This is followed by a summary of what is known of the distribution and …

ATP is the dominant messenger for astrocyte‐to‐astrocyte calcium‐mediated
communication. Definition of the exact ATP/P2 receptors in astrocytes and of their coupling …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …

The pyrimidines cytidine (as CTP) and uridine (which is converted to UTP and then CTP)
contribute to brain phosphatidylcholine and phosphatidylethanolamine synthesis via the …