Addictions to licit and illicit drugs are chronic relapsing brain disorders that affect circuits that
regulate reward, motivation, memory, and decision-making. Drug-induced pathological …

Although substantial advances have been made in behavioral and pharmacological
treatments for addictions, moving treatment development to the next stage may require novel …

BACKGROUND: Models of cocaine addiction emphasize the role of disrupted frontal
circuitry supporting cognitive control processes. However, addiction-related alterations in …

The ability to predict relapse is a major goal of drug addiction research. Clinical and
diagnostic measures are useful in this regard, but these measures do not fully and …

Individuals who abuse substances often differ from nonusers in their brain structure.
Substance abuse and addiction is often associated with atrophy and pathology of grey …

The five-factor model organizes personality traits into five factors: Neuroticism, Extraversion,
Openness to Experience, Agreeableness, and Conscientiousness. Measures of these …

Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in Iraq and
Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic mild TBI in military …

Importance Cocaine addiction is associated with altered resting-state functional connectivity
among regions of the mesocorticolimbic dopamine pathways. Methylphenidate …

Diffusion tractography allows identification and measurement of structural tracts in the
human brain previously associated with motivated behavior in animal models. Recent …

Internet gaming addiction (IGA) is increasingly recognized as a widespread disorder with
serious psychological and health consequences. Diminished white matter integrity has been …