The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Diffusion MRI (dMRI) is a unique tool for the study of brain circuitry, as it allows us to image
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …

Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …

Diffusion MRI is a non-invasive technique to study brain microstructure. Differences in the
microstructural properties of tissue, including size and anisotropy, can be represented in the …

Diffusion MRI uses the random displacement of water molecules to sensitize the signal to
brain microstructure and to properties such as the density and shape of cells. Microstructure …

Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

Abstract Characterization of porous media is essential in a wide range of biomedical and
industrial applications. Microstructural features can be probed non-invasively by diffusion …

Axon diameter mapping using high-gradient diffusion MRI has generated great interest as a
noninvasive tool for studying trends in axonal size in the human brain. One of the main …

To study axonal microstructure with diffusion MRI, axons are typically modeled as straight
impermeable cylinders, whereby the transverse diffusion MRI signal can be made sensitive …

Monitoring time dependence with diffusion MRI yields observables sensitive to compartment
sizes (restricted diffusion) and membrane permeability (water exchange). However …