Heme acquisition mechanisms of Porphyromonas gingivalis – strategies used in a polymicrobial community in a heme‐limited host environment

JW Smalley, T Olczak - Molecular Oral Microbiology, 2017 - Wiley Online Library
Porphyromonas gingivalis, a main etiologic agent and key pathogen responsible for
initiation and progression of chronic periodontitis requires heme as a source of iron and …

Gingipains from Porphyromonas gingivalis — complex domain structures confer diverse functions

N Li, CA Collyer - European Journal of Microbiology and …, 2011 - akjournals.com
Gingipains, a group of arginine or lysine specific cysteine proteinases (also known as RgpA,
RgpB and Kgp), have been recognized as major virulence factors in Porphyromonas …

Host immune responses to Porphyromonas gingivalis antigens.

RD Pathirana, NM O'Brien-Simpson… - Periodontology …, 2010 - search.ebscohost.com
The article discusses the major antigens of porphyromonas gingivalis, a gram-negative
bacteria which is found in the oral cavity. It is stated that the antigens induce an overall …

Microbial diversity and interactions in subgingival biofilm communities

PI Diaz - Periodontal disease, 2012 - karger.com
The human subgingival environment is a complex environmental niche where
microorganisms from the three domains of life meet to form diverse biofilm communities that …

Genome of the pathogen Porphyromonas gingivalis recovered from a biofilm in a hospital sink using a high-throughput single-cell genomics platform

JS McLean, MJ Lombardo, MG Ziegler… - Genome …, 2013 - genome.cshlp.org
Although biofilms have been shown to be reservoirs of pathogens, our knowledge of the
microbial diversity in biofilms within critical areas, such as health care facilities, is limited …

Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils

SA Castro, R Collighan, PA Lambert, IHK Dias… - Cell death & …, 2017 - nature.com
Periodontal disease is a prevalent chronic inflammatory condition characterised by an
aberrant host response to a pathogenic plaque biofilm resulting in local tissue damage and …

Heterogenic virulence and related factors among clinical isolates of Porphyromonas gingivalis with type II fimbriae

H Inaba, K Nakano, T Kato, R Nomura… - Oral microbiology …, 2008 - Wiley Online Library
Background/aims: Porphyromonas gingivalis is a periodontal pathogen whose fimbriae are
classified into six genotypes (types I–V and Ib) based on the diversity of the fimA genes …

Genotyping to distinguish microbial pathogenicity in periodontitis.

M Kuboniwa, H Inaba, A Amano - Periodontology 2000, 2010 - search.ebscohost.com
The article focuses on several genotyping assay methods used in determining the microbial
pathogenecity in periodontitis. It examines the genetic aspects of Porphyromonas gingivalis …

Cleavage of IgG1 in gingival crevicular fluid is associated with the presence of Porphyromonas gingivalis

A Guentsch, C Hirsch, W Pfister… - Journal of …, 2013 - Wiley Online Library
Background and Objectives Immunoglobulin (Ig) G1 plays an important role in the adaptive
immune response. Kgp, a lysine‐specific cysteine protease from P orphyromonas gingivalis …

The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis

N Li, P Yun, CM Jeffries, D Langley… - Molecular …, 2011 - Wiley Online Library
High‐molecular‐weight arginine‐and lysine‐specific (Kgp) gingipains are essential
virulence factors expressed by the oral pathogen Porphyromonas gingivalis …