Regulation of steroid hormone receptors and coregulators during the cell cycle highlights potential novel function in addition to roles as transcription factors
Y Zheng, LC Murphy - Nuclear receptor signaling, 2016 - journals.sagepub.com
Cell cycle progression is tightly controlled by several kinase families including Cyclin-
Dependent Kinases, Polo-Like Kinases, and Aurora Kinases. A large amount of data show …
Dependent Kinases, Polo-Like Kinases, and Aurora Kinases. A large amount of data show …
Structural insights into the inhibitor binding and new inhibitor design to Polo-like kinase-1 Polo-box domain using computational studies
M Abdullah, L Guruprasad - Journal of Biomolecular Structure and …, 2019 - Taylor & Francis
Polo box domain (PBD) from Polo-Like Kinase-1 (PLK-1) a cell cycle regulator is one of the
important non-kinase targets implicated in various cancers. The crystal structure of PLK-1 …
important non-kinase targets implicated in various cancers. The crystal structure of PLK-1 …
[PDF][PDF] Characterizing Oncogene Addiction in Alveolar Rhabdomyosarcoma to Find New Combination Therapies
J Ommer - 2018 - zora.uzh.ch
Pediatric cancer is the most common disease-related form of death in children and
adolescents. The advent of chemotherapy and radiotherapy in the middle of the last century …
adolescents. The advent of chemotherapy and radiotherapy in the middle of the last century …
[图书][B] Dissection of Phosphorylation Networks that Regulate Prometaphase Kinetochore-Microtubule Attachment Stability in Human Cells
AMG Dumitru - 2017 - search.proquest.com
The fidelity of chromosome segregation in mitosis is safeguarded by the precise regulation
of kinetochore microtubule (k-MT) attachment stability. The most abundant post-translational …
of kinetochore microtubule (k-MT) attachment stability. The most abundant post-translational …
Computational methods to analyze image-based siRNA knockdown screens
R Batra - 2013 - archiv.ub.uni-heidelberg.de
Neuroblastoma is the most common extra-cranial solid tumor of early childhood. Standard
therapies are not effective in case of poor prognosis and chemotherapy resistance. To …
therapies are not effective in case of poor prognosis and chemotherapy resistance. To …