Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by
pain, decline in function and reduced exercise tolerance. The most common overuse …

Connective tissue is one of the four major types of animal tissue and plays essential roles
throughout the human body. Genetic factors, aging, and trauma all contribute to connective …

Hydrogels that provide mechanical support and sustainably release therapeutics have been
used to treat tendon injuries. However, most hydrogels are insufficiently tough, release …

MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a
changing environment by modulating the cell transcriptome. miR-155 is a multifunctional …

Introduction The regulatory role of microRNA (miRNA) in several conditions has been
studied, but their function in tendon healing remains elusive. This review summarizes how …

MicroRNAs are small noncoding RNAs that can bind to the target sites in the 3'‐untranslated
region of messenger RNA to regulate posttranscriptional gene expression. Increasing …

Approved therapies for tendon diseases have not yet changed the clinical practice of
symptomatic pain treatment and physiotherapy. This review article summarizes advances in …

Background Exosomes are extracellular vesicles of nano-structures and represent an
emerging nano-scale acellular therapy in recent years. Tendon regeneration is a …

Following tendon injury, the development of fibrotic healing response impairs tendon
function and restricts tendon motion. Peritendinous tissue fibrosis poses a major clinical …

Background: Extracellular vesicles derived from mesenchymal stem cells (MSC-EVs) have
gained momentum as a treatment for tendinopathy. Multiple studies have demonstrated …