Engineering complex phenotypes in industrial strains
R Patnaik - Biotechnology Progress, 2008 - Wiley Online Library
The global demand is rising for greener manufacturing processes that are cost‐competitive
and available in a timely manner. This has led to the development of a series of new tools …
and available in a timely manner. This has led to the development of a series of new tools …
The Escherichia coli transcriptome mostly consists of independently regulated modules
AV Sastry, Y Gao, R Szubin, Y Hefner, S Xu… - Nature …, 2019 - nature.com
Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates
gene expression. A useful description of the TRN would decompose the transcriptome into …
gene expression. A useful description of the TRN would decompose the transcriptome into …
Multi-omics quantification of species variation of Escherichia coli links molecular features with strain phenotypes
Escherichia coli strains are widely used in academic research and biotechnology. New
technologies for quantifying strain-specific differences and their underlying contributing …
technologies for quantifying strain-specific differences and their underlying contributing …
So you want to express your protein in Escherichia coli?
AA Tungekar, A Castillo-Corujo… - Essays in …, 2021 - portlandpress.com
Recombinant proteins have been extensively employed as therapeutics for the treatment of
various critical and life-threatening diseases and as industrial enzymes in high-value …
various critical and life-threatening diseases and as industrial enzymes in high-value …
[HTML][HTML] Colanic acid biosynthesis in Escherichia coli is dependent on lipopolysaccharide structure and glucose availability
C Wang, H Zhang, J Wang, S Chen, Z Wang… - Microbiological …, 2020 - Elsevier
Lipopolysaccharide and colanic acid are important forms of exopolysaccharides located on
the cell surface of Escherichia coli, but their interrelation with the cell stress response is not …
the cell surface of Escherichia coli, but their interrelation with the cell stress response is not …
The evolution of metabolic networks of E. coli
DJ Baumler, RG Peplinski, JL Reed, JD Glasner… - BMC systems …, 2011 - Springer
Background Despite the availability of numerous complete genome sequences from E. coli
strains, published genome-scale metabolic models exist only for two commensal E. coli …
strains, published genome-scale metabolic models exist only for two commensal E. coli …
Synergetic Fermentation of Glucose and Glycerol for High-Yield N-Acetylglucosamine Production in Escherichia coli
K Wang, X Wang, H Luo, Y Wang, Y Wang… - International Journal of …, 2022 - mdpi.com
N-acetylglucosamine (GlcNAc) is an amino sugar that has been widely used in the
nutraceutical and pharmaceutical industries. Recently, microbial production of GlcNAc has …
nutraceutical and pharmaceutical industries. Recently, microbial production of GlcNAc has …
Nitrogen and Carbon Status Are Integrated at the Transcriptional Level by the Nitrogen Regulator NtrC In Vivo
J Schumacher, V Behrends, Z Pan, DR Brown… - MBio, 2013 - Am Soc Microbiol
Nitrogen regulation in Escherichia coli is a model system for gene regulation in bacteria.
Growth on glutamine as a sole nitrogen source is assumed to be nitrogen limiting, inferred …
Growth on glutamine as a sole nitrogen source is assumed to be nitrogen limiting, inferred …
Transcriptional effects of CRP* expression in Escherichia coli
Background Escherichia coli exhibits diauxic growth in sugar mixtures due to CRP-mediated
catabolite repression and inducer exclusion related to phosphotransferase system enzyme …
catabolite repression and inducer exclusion related to phosphotransferase system enzyme …
[HTML][HTML] RapidRIP quantifies the intracellular metabolome of 7 industrial strains of E. coli
D McCloskey, J Xu, L Schrübbers, HB Christensen… - Metabolic …, 2018 - Elsevier
Fast metabolite quantification methods are required for high throughput screening of
microbial strains obtained by combinatorial or evolutionary engineering approaches. In this …
microbial strains obtained by combinatorial or evolutionary engineering approaches. In this …