Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor
subtype,–. To identify novel loci, we performed a genome-wide association study including …
subtype,–. To identify novel loci, we performed a genome-wide association study including …
Pathology of tumors associated with pathogenic germline variants in 9 breast cancer susceptibility genes
Importance Rare germline genetic variants in several genes are associated with increased
breast cancer (BC) risk, but their precise contributions to different disease subtypes are …
breast cancer (BC) risk, but their precise contributions to different disease subtypes are …
[HTML][HTML] Diesel exhaust and bladder cancer risk by pathologic stage and grade subtypes
S Koutros, M Kogevinas, MC Friesen, PA Stewart… - Environment …, 2020 - Elsevier
Abstract Background The International Agency for Research on Cancer (IARC) classifies
diesel engine exhaust as carcinogenic to humans based on sufficient evidence for lung …
diesel engine exhaust as carcinogenic to humans based on sufficient evidence for lung …
Genetic interactions effects for cancer disease identification using computational models: a review
R Manavalan, S Priya - Medical & Biological Engineering & Computing, 2021 - Springer
Genome-wide association studies (GWAS) provide clear insight into understanding genetic
variations and environmental influences responsible for various human diseases. Cancer …
variations and environmental influences responsible for various human diseases. Cancer …
Cis-and trans-eQTL TWASs of breast and ovarian cancer identify more than 100 susceptibility genes in the BCAC and OCAC consortia
Transcriptome-wide association studies (TWASs) have investigated the role of genetically
regulated transcriptional activity in the etiologies of breast and ovarian cancer. However …
regulated transcriptional activity in the etiologies of breast and ovarian cancer. However …
Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Background Genome-wide association studies (GWAS) have identified multiple common
breast cancer susceptibility variants. Many of these variants have differential associations by …
breast cancer susceptibility variants. Many of these variants have differential associations by …
[HTML][HTML] Cis-and trans-eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortia
ST Head, F Dezem, A Todor, J Yang, J Plummer… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Transcriptome-wide association studies (TWAS) have investigated the role of genetically
regulated transcriptional activity in the etiologies of breast and ovarian cancer. However …
regulated transcriptional activity in the etiologies of breast and ovarian cancer. However …
Nitrated polycyclic aromatic hydrocarbon (nitro-PAH) signatures and somatic mutations in diesel exhaust-exposed bladder tumors
Background: Diesel exhaust is a complex mixture, including polycyclic aromatic
hydrocarbons (PAH) and nitrated PAHs (nitro-PAH), many of which are potent mutagens and …
hydrocarbons (PAH) and nitrated PAHs (nitro-PAH), many of which are potent mutagens and …
A Linear Relationship between the Number of Cancers among First-Degree Relatives and the Risk of Multiple Primary Cancers
With advances in the early detection and treatment of cancer, the incidence of multiple
primary cancers (MPC) or second primary cancers has increased over time …
primary cancers (MPC) or second primary cancers has increased over time …
[PDF][PDF] Common breast cancer risk loci predispose to distinct tumor subtypes
TU Ahearn, H Zhang, K Michailidou, RL Milne… - bioRxiv, 2019 - academia.edu
Breast cancer represents a heterogenous group of diseases with different molecular and
clinical features [1]. Clinical assessment of estrogen receptor (ER), progesterone receptor …
clinical features [1]. Clinical assessment of estrogen receptor (ER), progesterone receptor …