Nonspecific low back pain

A Chiarotto, BW Koes - New England Journal of Medicine, 2022 - Mass Medical Soc
Key Clinical Points Nonspecific Low Back Pain Nonspecific low back pain is diagnosed on
the basis of the exclusion of specific causes, usually by means of history taking and physical …

What low back pain is and why we need to pay attention

J Hartvigsen, MJ Hancock, A Kongsted, Q Louw… - The Lancet, 2018 - thelancet.com
Low back pain is a very common symptom. It occurs in high-income, middle-income, and low-
income countries and all age groups from children to the elderly population. Globally, years …

[HTML][HTML] The Lancet Series call to action to reduce low value care for low back pain: an update

R Buchbinder, M Underwood, J Hartvigsen, CG Maher - Pain, 2020 - journals.lww.com
The 2018 Lancet Low Back Pain Series, comprising 3 papers written by 31 authors from
disparate disciplines and 12 different countries, raised unprecedented awareness of the …

Fundamentals of intervertebral disc degeneration

S Kirnaz, C Capadona, T Wong, JL Goldberg… - World neurosurgery, 2022 - Elsevier
Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …

Cognitive functional therapy compared with a group-based exercise and education intervention for chronic low back pain: a multicentre randomised controlled trial …

M O'Keeffe, P O'Sullivan, H Purtill, N Bargary… - British journal of sports …, 2020 - bjsm.bmj.com
Background One-size-fits-all interventions reduce chronic low back pain (CLBP) a small
amount. An individualised intervention called cognitive functional therapy (CFT) was …

[HTML][HTML] Modic changes—their associations with low back pain and activity limitation: a systematic literature review and meta-analysis

C Herlin, P Kjaer, A Espeland, JS Skouen… - PloS one, 2018 - journals.plos.org
Background Previous systematic reviews have reported positive associations between
Modic changes (MCs) and low back pain (LBP), but due to their narrow scope and new …

[HTML][HTML] Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

Y Song, S Li, W Geng, R Luo, W Liu, J Tu, K Wang… - Redox biology, 2018 - Elsevier
Intervertebral disc (IVD) degeneration contributes largely to pathoanatomical and
degenerative changes of spinal structure that increase the risk of low back pain. Apoptosis in …

Diagnosis and treatment of sciatica

RK Jensen, A Kongsted, P Kjaer, B Koes - Bmj, 2019 - bmj.com
Diagnosis and treatment of sciatica | The BMJ Skip to main content Intended for healthcare
professionals Access provided by Google Indexer Subscribe My Account My email alerts BMA …

[HTML][HTML] The role of structure and function changes of sensory nervous system in intervertebral disc-related low back pain

S Zhang, B Hu, W Liu, P Wang, X Lv, S Chen… - Osteoarthritis and …, 2021 - Elsevier
Low back pain (LBP) is a common musculoskeletal symptom, which can be developed in
multiple clinical diseases. It is widely recognized that intervertebral disc (IVD) degeneration …

[HTML][HTML] Association of lumbar MRI findings with current and future back pain in a population-based cohort study

R Kasch, J Truthmann, MJ Hancock, CG Maher, M Otto… - Spine, 2022 - journals.lww.com
Study Design. Population-based cohort study. Objective. We examined associations
between common lumbar degenerative changes observed on magnetic resonance imaging …