[HTML][HTML] Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices
Culture of cells using various microfluidic devices is becoming more common within
experimental cell biology. At the same time, a technological radiation of microfluidic cell …
experimental cell biology. At the same time, a technological radiation of microfluidic cell …
Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease
Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …
the development of organ-on-a-chip devices that can reproduce key functions of various …
[HTML][HTML] Small but perfectly formed? Successes, challenges, and opportunities for microfluidics in the chemical and biological sciences
Microfluidic systems are pervasive in many areas of experimental science, but what are the
real advantages of this technology? We describe some of the features and properties that …
real advantages of this technology? We describe some of the features and properties that …
Organ‐on‐a‐Chip Systems: microengineering to biomimic living systems
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …
biomimetic principles to create key aspects of living organs faithfully, including critical …
[HTML][HTML] Integrating biosensors in organs-on-chip devices: A perspective on current strategies to monitor microphysiological systems
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced
in vitro tools able to replicate essential functions of human organs. Owing to their …
in vitro tools able to replicate essential functions of human organs. Owing to their …
Build your own soil: exploring microfluidics to create microbial habitat structures
Soil is likely the most complex ecosystem on earth. Despite the global importance and
extraordinary diversity of soils, they have been notoriously challenging to study. We show …
extraordinary diversity of soils, they have been notoriously challenging to study. We show …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
[HTML][HTML] Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia
I Bahrini, J Song, D Diez, R Hanayama - Scientific reports, 2015 - nature.com
Selective elimination of synaptic connections is a common phenomenon which occurs
during both developmental and pathological conditions. Glial cells have a central role in the …
during both developmental and pathological conditions. Glial cells have a central role in the …
[HTML][HTML] Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition
KS Dittlau, EN Krasnow, L Fumagalli, T Vandoorne… - Stem Cell Reports, 2021 - cell.com
Neuromuscular junctions (NMJs) ensure communication between motor neurons (MNs) and
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …
[HTML][HTML] Modeling gut neuro-epithelial connections in a novel microfluidic device
JM de Hoyos-Vega, X Yu… - Microsystems & …, 2023 - nature.com
The intestinal lumen is filled with diverse chemical and physical stimuli. Intestinal epithelial
cells sense these stimuli and signal to enteric neurons which coordinate a range of …
cells sense these stimuli and signal to enteric neurons which coordinate a range of …