Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …

Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …

This study aims to design and optimize chitosan-coated bilosomal formulations loaded with
psoralidin (Ps-CS/BLs) with improved physicochemical properties, oral bioavailability, and …

Background The tumor microenvironment (TME) represents a barrier to PDT efficacy among
melanoma patients. The aim of this study is to employ a novel muti-tactic TME-remodeling …

To provide precise medical regimens, photonics technologies have been involved in the
field of nanomedicine. Phototriggered liposomes have been cast as promising nanosystems …

A non-negligible part of our DNA has been proven to be transcribed into non-protein coding
RNA and its intricate involvement in several physiological processes has been highly …

Recently, myriad studies have defined the versatile abilities of gasotransmitters and their
synthesizing enzymes to play a “Maestro” role in orchestrating several oncological and non …

The discovery of non-coding RNAs (ncRNAs) has unveiled a wide range of transcripts that
do not encode proteins but play key roles in several cellular and molecular processes. Long …

Evidence suggests that long non-coding RNAs (lncRNAs) play a pivotal role in the
carcinogenesis and progression of various human malignancies including gastrointestinal …

The concept of 'Hallmarks of Cancer'is an approach of reducing the enormous complexity of
cancer to a set of guiding principles. As the underlying mechanism of cancer are portrayed …