Tissue clearing
DS Richardson, W Guan, K Matsumoto, C Pan… - Nature Reviews …, 2021 - nature.com
Tissue clearing of gross anatomical samples was first described more than a century ago
and has only recently found widespread use in the field of microscopy. This renaissance has …
and has only recently found widespread use in the field of microscopy. This renaissance has …
Whole-brain profiling of cells and circuits in mammals by tissue clearing and light-sheet microscopy
Tissue clearing and light-sheet microscopy have a 100-year-plus history, yet these fields
have been combined only recently to facilitate novel experiments and measurements in …
have been combined only recently to facilitate novel experiments and measurements in …
Atlas-based data integration for mapping the connections and architecture of the brain
TB Leergaard, JG Bjaalie - Science, 2022 - science.org
Detailed knowledge about the neural connections among regions of the brain is key for
advancing our understanding of normal brain function and changes that occur with aging …
advancing our understanding of normal brain function and changes that occur with aging …
Microtubule-binding protein MAP1B regulates interstitial axon branching of cortical neurons via the tubulin tyrosination cycle
J Ziak, JM Dorskind, B Trigg, S Sudarsanam… - The EMBO …, 2024 - embopress.org
Regulation of directed axon guidance and branching during development is essential for the
generation of neuronal networks. However, the molecular mechanisms that underlie …
generation of neuronal networks. However, the molecular mechanisms that underlie …
Evolving characterization of the human hyperdirect pathway
The hyperdirect pathway (HDP) represents the main glutamatergic input to the subthalamic
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …
[HTML][HTML] Microfluidic platforms for single neuron analysis
Single-neuron actions are the basis of brain function, as clinical sequelae, neuronal
dysfunction or failure for most of the central nervous system (CNS) diseases and injuries can …
dysfunction or failure for most of the central nervous system (CNS) diseases and injuries can …
Multi-scale model of axonal and dendritic polarization by transcranial direct current stimulation in realistic head geometry
Background Transcranial direct current stimulation (tDCS) is a non-invasive brain
stimulation modality that can alter cortical excitability. However, it remains unclear how the …
stimulation modality that can alter cortical excitability. However, it remains unclear how the …
What we can learn from the complex architecture of single axons
KS Rockland - Brain Structure and Function, 2020 - Springer
Anterogradely labeled connections at the single-axon level provide unparalleled spatial and
quantitative data as well as a novel perspective on laminar, columnar, hierarchical and other …
quantitative data as well as a novel perspective on laminar, columnar, hierarchical and other …
A single-neuron: Current trends and future prospects
The brain is an intricate network with complex organizational principles facilitating a
concerted communication between single-neurons, distinct neuron populations, and remote …
concerted communication between single-neurons, distinct neuron populations, and remote …
Seeing the forest and its trees together: implementing 3D light microscopy pipelines for cell type mapping in the mouse brain
KT Newmaster, FA Kronman, Y Wu… - Frontiers in neuroanatomy, 2022 - frontiersin.org
The brain is composed of diverse neuronal and non-neuronal cell types with complex
regional connectivity patterns that create the anatomical infrastructure underlying cognition …
regional connectivity patterns that create the anatomical infrastructure underlying cognition …