Biological functions and applications of LncRNAs in the regulation of the extracellular matrix in osteoarthritis
D Shi, Y Mei, W Hao, J Li, S Liu, X Lin - Frontiers in Cell and …, 2024 - frontiersin.org
Osteoarthritis (OA) is a major cause of disability, characterized by chronic pain, irreversible
destruction, and loss of function of the articular cartilage. The integrity and arrangement of …
destruction, and loss of function of the articular cartilage. The integrity and arrangement of …
Emerging role of lncRNAs in osteoarthritis: An updated review
R Wang, HT Shiu, WYW Lee - Frontiers in immunology, 2022 - frontiersin.org
Osteoarthritis (OA) is a prevalent joint disease, which is associated with progressive articular
cartilage loss, synovial inflammation, subchondral sclerosis and meniscus injury. The …
cartilage loss, synovial inflammation, subchondral sclerosis and meniscus injury. The …
Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis
R Coutinho de Almeida, M Tuerlings, Y Ramos… - …, 2023 - academic.oup.com
Objectives To present an unbiased approach to identify positional transcript single
nucleotide polymorphisms (SNPs) of osteoarthritis (OA) risk loci by allelic expression …
nucleotide polymorphisms (SNPs) of osteoarthritis (OA) risk loci by allelic expression …
Long non-coding RNA PVT1 and its target miRNA-146a as potential prognostic biomarkers in rheumatoid arthritis patients
R Erfan, OG Shaker, MAF Khalil, YA Elsabagh… - Life, 2021 - mdpi.com
Objective: Long non-coding RNAs (lncRNAs) and their target microRNAs were documented
in multiple studies to have a significant role in different joint disorders such as rheumatoid …
in multiple studies to have a significant role in different joint disorders such as rheumatoid …
A Damaging COL6A3 Variant Alters the MIR31HG‐Regulated Response of Chondrocytes in Neocartilage Organoids to Hyperphysiologic Mechanical Loading
The pericellular matrix (PCM), with its hallmark proteins collagen type VI (COLVI) and
fibronectin (FN), surrounds chondrocytes and is critical in transducing the biomechanical …
fibronectin (FN), surrounds chondrocytes and is critical in transducing the biomechanical …
Comprehensive analysis on subchondral bone marrow lesions of human osteoarthritis by integrating bulk and single-cell transcriptomes
M Zeng, X Wang, T Chen, G Ruan, J Li, S Xue… - BMC Musculoskeletal …, 2023 - Springer
Objective This study aims to demonstrate the cellular composition and underlying
mechanisms in subchondral bone marrow lesions (BMLs) of knee osteoarthritis (OA) …
mechanisms in subchondral bone marrow lesions (BMLs) of knee osteoarthritis (OA) …
[HTML][HTML] RNA-seq identifies differentially expressed genes involved in csal1 overexpression in granulosa cells of prehierarchical follicles in Chinese Dagu hens
H Zhu, Y Ding, J Zhu, L Zhao, Y Su, S Zhao - Poultry Science, 2023 - Elsevier
The transcription factor csal1 is an important molecule that plays a critical regulatory function
in ovarian follicle development, as confirmed by our previous data. However, the candidate …
in ovarian follicle development, as confirmed by our previous data. However, the candidate …
Coding and noncoding RNA profile of human heterotopic ossifications-Risk factors and biomarkers
B Mierzejewski, Ł Pulik, I Grabowska, A Sibilska… - Bone, 2023 - Elsevier
Heterotopic ossification (HO) means the formation of bone in muscles and soft tissues, such
as ligaments or tendons. HO could have a genetic history or develop after a traumatic event …
as ligaments or tendons. HO could have a genetic history or develop after a traumatic event …
Unraveling the Molecular Landscape of Osteoarthritis: A Comprehensive Review Focused on the Role of Non-Coding RNAs
M Shakeri, A Aminian, K Mokhtari, M Bahaeddini… - … -Research and Practice, 2024 - Elsevier
Osteoarthritis (OA) poses a significant global health challenge, with its prevalence
anticipated to increase in the coming years. This review delves into the emerging molecular …
anticipated to increase in the coming years. This review delves into the emerging molecular …
LncRNA AC005165. 1 Alleviates IL-1β-Induced Osteoarthritis via miR-199a-3p/TXNIP Axis
X Gu, T Xie - Biochemical Genetics, 2024 - Springer
Osteoarthritis (OA) is a chronic musculoskeletal disease and often causes impaired joint
mobility and disability. Long noncoding RNAs (lncRNAs) play pivotal roles in OA …
mobility and disability. Long noncoding RNAs (lncRNAs) play pivotal roles in OA …