General mechanisms of weak acid-tolerance and current strategies for the development of tolerant yeasts

M Li, Y Chu, X Dong, H Ji - World Journal of Microbiology and …, 2024 - Springer
Yeast cells are often subjected to various types of weak acid stress in the process of
industrial production, food processing, and preservation, resulting in growth inhibition and …

[HTML][HTML] Phosphoregulation of the yeast Pma1 H+-ATPase autoinhibitory domain involves the Ptk1/2 kinases and the Glc7 PP1 phosphatase and is under TORC1 …

N Guarini, E Saliba, B André - PLoS Genetics, 2024 - journals.plos.org
Plasma membrane (PM) H+-ATPases of the P-type family are highly conserved in yeast,
other fungi, and plants. Their main role is to establish an H+ gradient driving active transport …

[HTML][HTML] The Hrk1 kinase is a determinant of acetic acid tolerance in yeast by modulating H+ and K+ homeostasis

M Antunes, D Kale, H Sychrová, I Sá-Correia - Microbial Cell, 2023 - ncbi.nlm.nih.gov
Acetic acid-induced stress is a common challenge in natural environments and industrial
bioprocesses, significantly affecting the growth and metabolic performance of …

Perspectives on the specific targeting of Fusarium graminearum for the development of alternative head blight treatment approaches

M Cuperlovic‐Culf, M Loewen, N Rajagopalan… - Plant …, 2017 - Wiley Online Library
Diseases of agricultural crops caused by fungi have devastating economic and health
effects. Fusarium head blight (FHB) is one of the most damaging diseases of wheat and …

Specific phosphoantibodies reveal two phosphorylation sites in yeast Pma1 in response to glucose

MJ Mazón, P Eraso, F Portillo - FEMS Yeast Research, 2015 - academic.oup.com
Glucose triggers post-translational modifications of the Saccharomyces cerevisiae plasma
membrane H+-ATPase (Pma1) that lead to an increase in enzyme activity. The activation …

[HTML][HTML] Fusarium graminearum pyruvate dehydrogenase kinase 1 (FgPDK1) Is Critical for Conidiation, Mycelium Growth, and Pathogenicity

T Gao, J Chen, Z Shi - PLoS One, 2016 - journals.plos.org
Pyruvate dehydrogenase kinase (PDK) is an important mitochondrial enzyme that blocks the
production of acetyl-CoA by selectively inhibiting the activity of pyruvate dehydrogenase …

[HTML][HTML] Membrane phosphoproteomics of yeast early response to acetic acid: role of Hrk1 kinase and lipid biosynthetic pathways, in particular sphingolipids

JF Guerreiro, NP Mira, AXS Santos… - Frontiers in …, 2017 - frontiersin.org
Saccharomyces cerevisiae response and tolerance to acetic acid is critical in industrial
biotechnology and in acidic food and beverages preservation. The HRK1 gene, encoding a …

Genomic approachesidentifySTT4 as a new component in glucose-induced activation of yeast plasma membrane H+-ATPase

PGP Barbosa, I Rosse, DF Silva, MAF Saraiva… - Cell Calcium, 2024 - Elsevier
Many studies have focused on identifying the signaling pathway by which addition of
glucose triggers post-translational activation of the plasma membrane H+-ATPase in yeast …

[HTML][HTML] The NPR/Hal family of protein kinases in yeasts: biological role, phylogeny and regulation under environmental challenges

M Antunes, I Sá-Correia - Computational and Structural Biotechnology …, 2022 - Elsevier
Protein phosphorylation is the most common and versatile post-translational modification
occurring in eukaryotes. In yeast, protein phosphorylation is fundamental for maintaining cell …

Lpx1p links glucose-induced calcium signaling and plasma membrane H+-ATPase activation in Saccharomyces cerevisiae cells

DD Castanheira, EP Santana… - FEMS yeast …, 2018 - academic.oup.com
In yeast, as in other eukaryotes, calcium plays an essential role in signaling transduction to
regulate different processes. Many pieces of evidence suggest that glucose-induced …