Novel insight into RNA modifications in tumor immunity: Promising targets to prevent tumor immune escape
An immunosuppressive state is a typical feature of the tumor microenvironment. Despite the
dramatic success of immune checkpoint inhibitor (ICI) therapy in preventing tumor cell …
dramatic success of immune checkpoint inhibitor (ICI) therapy in preventing tumor cell …
Writers, readers, and erasers RNA modifications and drug resistance in cancer
D Chen, X Gu, Y Nurzat, L Xu, X Li, L Wu, H Jiao… - Molecular Cancer, 2024 - Springer
Drug resistance in cancer cells significantly diminishes treatment efficacy, leading to
recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic …
recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic …
m6A-Atlas v2.0: updated resources for unraveling the N6-methyladenosine (m6A) epitranscriptome among multiple species
Abstract N 6-Methyladenosine (m6A) is one of the most abundant internal chemical
modifications on eukaryote mRNA and is involved in numerous essential molecular …
modifications on eukaryote mRNA and is involved in numerous essential molecular …
m7GHub V2.0: an updated database for decoding the N7-methylguanosine (m7G) epitranscriptome
With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of
thousands of experimentally validated m7G sites have been discovered in various species …
thousands of experimentally validated m7G sites have been discovered in various species …
XGBoost framework with feature selection for the prediction of RNA N5-methylcytosine sites
5-methylcytosine (m5C) is indeed a critical post-transcriptional alteration that is widely
present in various kinds of RNAs and is crucial to the fundamental biological processes. By …
present in various kinds of RNAs and is crucial to the fundamental biological processes. By …
The functions and mechanisms of post-translational modification in protein regulators of RNA methylation: Current status and future perspectives
Y Chen, Z Jiang, Y Yang, C Zhang, H Liu… - International Journal of …, 2023 - Elsevier
RNA methylation, an epigenetic modification that does not alter gene sequence, may be
important to diverse biological processes. Protein regulators of RNA methylation include …
important to diverse biological processes. Protein regulators of RNA methylation include …
An ontology-based knowledge graph for representing interactions involving RNA molecules
The “RNA world” represents a novel frontier for the study of fundamental biological
processes and human diseases and is paving the way for the development of new drugs …
processes and human diseases and is paving the way for the development of new drugs …
Exploring N6-methyladenosine (m6A) modification in tree species: opportunities and challenges
Abstract N 6-methyladenosine (m6A) in eukaryotes is the most common and widespread
internal modification in mRNA. The modification regulates mRNA stability, translation …
internal modification in mRNA. The modification regulates mRNA stability, translation …
Sci-ModoM: a quantitative database of transcriptome-wide high-throughput RNA modification sites
E Boileau, H Wilhelmi, A Busch… - Nucleic Acids …, 2025 - academic.oup.com
Abstract We present Sci-ModoM, the first next-generation RNome database offering a
holistic view of the epitranscriptomic landscape. Sci-ModoM has a simple yet powerful …
holistic view of the epitranscriptomic landscape. Sci-ModoM has a simple yet powerful …
EMDL-ac4C: identifying N4-acetylcytidine based on ensemble two-branch residual connection DenseNet and attention
J Jia, Z Wei, X Cao - Frontiers in Genetics, 2023 - frontiersin.org
Introduction: N4-acetylcytidine (ac4C) is a critical acetylation modification that has an
essential function in protein translation and is associated with a number of human diseases …
essential function in protein translation and is associated with a number of human diseases …