Psychedelic therapy has witnessed a resurgence in interest in the last decade from the
scientific and medical communities with evidence now building for its safety and efficacy in …

Psychedelic compounds have shown extraordinary potential in treating a wide range of
neuropsychiatric disorders. Psilocybin, for example, has now been shown in several clinical …

Importance Although classic psychedelic medications have shown promise in the treatment
of alcohol use disorder (AUD), the efficacy of psilocybin remains unknown. Objective To …

Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in
synaptic function are prominent among these effects. Acute exposure to EtOH activates or …

Recent clinical and preclinical evidence suggests that psychedelics and entactogens may
produce both rapid and sustained therapeutic effects across several indications. Currently …

Alcohol abuse is a leading risk factor for the public health burden worldwide. Approved
pharmacotherapies have demonstrated limited effectiveness over the last few decades in …

Psilocybin and other serotonergic psychedelics have re-emerged as therapeutics for
neuropsychiatric disorders, including addiction. Psilocybin induces long-lasting effects on …

The potential of psychedelics to persistently treat substance use disorders is known since
the 1960s. However, the biological mechanisms responsible for their therapeutic effects …

Accumulating clinical evidence shows that psychedelic therapy, by synergistically combining
psychopharmacology and psychological support, offers a promising transdiagnostic …

Classic psychedelics refer to substances such as lysergic acid diethylamide (LSD),
psilocybin, ayahuasca, and mescaline, which induce altered states of consciousness by …