Severe influenza infection represents a leading cause of global morbidity and mortality.
Although influenza is primarily considered a viral infection that results in pathology limited to …

Febrile seizures are one of the commonest presentations in young children, with a 2–5%
incidence in Western countries. Though they are generally benign, with rare long-term …

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, creates an urgent
need for identifying molecular mechanisms that mediate viral entry, propagation, and tissue …

We reviewed the epidemiology, clinical characteristics, disease severity, and economic
burden of influenza B as reported in the peer-reviewed published literature. We used …

Acute necrotizing encephalopathy (ANE) is a rare but distinctive type of acute
encephalopathy with global distribution. Occurrence of ANE is usually preceded by a virus …

The pathology of human influenza has been studied most intensively during the three
pandemics of the last century, the last of which occurred in 1968. It is important to revisit this …

Inflammatory signals generated within the brain and peripheral nervous system direct
diverse biological processes. Key amongst the inflammatory molecules is tumor necrosis …

Inflammation is known to participate in the mediation of a growing number of acute and
chronic neurological disorders. Even so, the involvement of inflammation in the …

Influenza A viruses (IAVs) can be classified into dozens of subtypes based on their
hemagglutinin (HA) and neuraminidase (NA) proteins. To date, 18 HA subtypes and 11 NA …

Background. Severe influenza is characterized by cytokine storm and multiorgan failure with
edema. The aim of this study was to define the impact of the cytokine storm on the …