How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis?
PM Preshaw, JJ Taylor - Journal of clinical periodontology, 2011 - Wiley Online Library
Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …
A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17
SL Gaffen, G Hajishengallis - Journal of dental research, 2008 - journals.sagepub.com
For almost two decades, the Th1/Th2 paradigm has offered a productive conceptual
framework for investigating the pathogenesis of periodontitis. However, as with many other …
framework for investigating the pathogenesis of periodontitis. However, as with many other …
Cytokine Profiling of Macrophages Exposed to Porphyromonas gingivalis, Its Lipopolysaccharide, or Its FimA Protein
Q Zhou, T Desta, M Fenton, DT Graves… - Infection and …, 2005 - Am Soc Microbiol
To characterize the roles of Porphyromonas gingivalis and its components in the disease
processes, we investigated the cytokine profile induced by live P. gingivalis, its …
processes, we investigated the cytokine profile induced by live P. gingivalis, its …
Heat shock proteins as endogenous adjuvants in sterile and septic inflammation
FJ Quintana, IR Cohen - The journal of immunology, 2005 - journals.aai.org
Heat shock proteins (HSPs) have been reported to stimulate the immune system via innate
receptors. However, the role of HSPs as endogenous adjuvants has been challenged by …
receptors. However, the role of HSPs as endogenous adjuvants has been challenged by …
Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and …
TDK Herath, RP Darveau, CJ Seneviratne, CY Wang… - PloS one, 2013 - journals.plos.org
Background Porphyromonas gingivalis is a major pathogen of periodontal disease that
affects a majority of adults worldwide. Increasing evidence shows that periodontal disease is …
affects a majority of adults worldwide. Increasing evidence shows that periodontal disease is …
MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex
SR Coats, TTT Pham, BW Bainbridge… - The Journal of …, 2005 - journals.aai.org
We have demonstrated previously that tetra-acylated LPS derived from the oral bacterium,
Porphyromonas gingivalis, and penta-acylated msbB LPS derived from a mutant strain of …
Porphyromonas gingivalis, and penta-acylated msbB LPS derived from a mutant strain of …
Peripheral blood neutrophil cytokine hyper-reactivity in chronic periodontitis
MR Ling, ILC Chapple, JB Matthews - Innate immunity, 2015 - journals.sagepub.com
Pro-inflammatory cytokine release (IL-8, IL-6, TNF-α, IL-1β) by peripheral blood neutrophils,
isolated from periodontitis patients (before/after therapy) and matched controls, was …
isolated from periodontitis patients (before/after therapy) and matched controls, was …
Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll‐like receptor 2‐centred pattern recognition apparatus
G Hajishengallis, RI Tapping… - Cellular …, 2006 - Wiley Online Library
The lipopolysaccharide (LPS) and fimbriae of Porphyromonas gingivalis play important roles
in periodontal inflammation and pathogenesis. We investigated fimbriae and LPS from …
in periodontal inflammation and pathogenesis. We investigated fimbriae and LPS from …
Nisin lantibiotic prevents NAFLD liver steatosis and mitochondrial oxidative stress following periodontal disease by abrogating oral, gut and liver dysbiosis
R Kuraji, C Ye, C Zhao, L Gao, A Martinez… - npj Biofilms and …, 2024 - nature.com
Oral microbiome dysbiosis mediates chronic periodontal disease, gut microbial dysbiosis,
and mucosal barrier disfunction that leads to steatohepatitis via the enterohepatic …
and mucosal barrier disfunction that leads to steatohepatitis via the enterohepatic …
Lipopolysaccharides from atherosclerosis‐associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2‐induced …
M Triantafilou, FGJ Gamper, PM Lepper… - Cellular …, 2007 - Wiley Online Library
Infection with bacteria such as Chlamydia pneumonia, Helicobacter pylori or
Porphyromonas gingivalis may be triggering the secretion of inflammatory cytokines that …
Porphyromonas gingivalis may be triggering the secretion of inflammatory cytokines that …