Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex

S Ikemoto - Brain research reviews, 2007 - Elsevier
Anatomical and functional refinements of the meso-limbic dopamine system of the rat are
discussed. Present experiments suggest that dopaminergic neurons localized in the …

The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking

S Ikemoto, J Panksepp - Brain Research Reviews, 1999 - Elsevier
Studies addressing behavioral functions of dopamine (DA) in the nucleus accumbens septi
(NAS) are reviewed. A role of NAS DA in reward has long been suggested. However, some …

Conditioned place preference: what does it add to our preclinical understanding of drug reward?

MT Bardo, RA Bevins - Psychopharmacology, 2000 - Springer
Rationale: Among the various experimental protocols that have been used to measure drug
reward in laboratory animals, conditioned place preference (CPP) has been one of the most …

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

TM Tzschentke - Progress in neurobiology, 1998 - Elsevier
This review gives an overview of recent findings and developments in research on brain
mechanisms of reward and reinforcement from studies using the place preference …

[HTML][HTML] Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events

JC Horvitz - Neuroscience, 2000 - Elsevier
While it has previously been assumed that mesolimbic dopamine neurons carry a reward
signal, recent data from single-unit, microdialysis and voltammetry studies suggest that …

The neurobiology of positive emotions

J Burgdorf, J Panksepp - Neuroscience & Biobehavioral Reviews, 2006 - Elsevier
Compared to the study of negative emotions such as fear, the neurobiology of positive
emotional processes and the associated positive affect (PA) states has only recently …

Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective

A Alcaro, R Huber, J Panksepp - Brain research reviews, 2007 - Elsevier
The mesolimbic dopaminergic (ML-DA) system has been recognized for its central role in
motivated behaviors, various types of reward, and, more recently, in cognitive processes …

Intra-accumbens amphetamine increases the conditioned incentive salience of sucrose reward: enhancement of reward “wanting” without enhanced “liking” or …

CL Wyvell, KC Berridge - Journal of Neuroscience, 2000 - Soc Neuroscience
Amphetamine microinjection into the nucleus accumbens shell enhanced the ability of a
Pavlovian reward cue to trigger increased instrumental performance for sucrose reward in a …

Psychobiology of novelty seeking and drug seeking behavior

MT Bardo, RL Donohew, NG Harrington - Behavioural brain research, 1996 - Elsevier
There is considerable evidence that high novelty seekers are at increased risk for using
drugs of abuse relative to low novelty seekers. This review examines the potential biological …

A gender-specific mechanism for pair bonding: oxytocin and partner preference formation in monogamous voles.

TR Insel, TJ Hulihan - Behavioral neuroscience, 1995 - psycnet.apa.org
Previous studies have demonstrated that central administration of vasopressin but not
oxytocin facilitates pair bonding in the monogamous male prairie vole. This study tested …