CAR T-cell therapy for B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia: clinical trials and real-world experiences

C Vitale, P Strati - Frontiers in oncology, 2020 - frontiersin.org
Chimeric antigen receptor-modified (CAR) T cells targeting CD19 have revolutionized the
treatment of relapsed or refractory aggressive B-cell lymphomas, and their use has …

Circulating tumor DNA in lymphoma: principles and future directions

M Roschewski, D Rossi, DM Kurtz, AA Alizadeh… - Blood Cancer …, 2022 - AACR
Lymphomas are heterogeneous tumors with striking genetic diversity and variable outcomes
even within pathologic diagnoses. Treatment response assessment relies on radiologic and …

Prognostic impact of total metabolic tumor volume in large B-cell lymphoma patients receiving CAR T-cell therapy

G Iacoboni, M Simó, G Villacampa, E Catalá… - Annals of …, 2021 - Springer
Chimeric antigen receptor (CAR) T-cell therapy provides long-term remissions in patients
with relapsed or refractory (R/R) large B-cell lymphoma (LBCL). Total metabolic tumor …

[HTML][HTML] Cellular immunotherapy for refractory diffuse large B cell lymphoma in the chimeric antigen receptor-engineered T cell era: still a role for allogeneic …

P Dreger, TS Fenske, S Montoto, MC Pasquini… - Biology of Blood and …, 2020 - Elsevier
Chimeric antigen receptor-engineered T (CART) cells are a promising new treatment option
for patients with multiply relapsed and refractory (R/R) diffuse large B cell lymphoma …

CAR‐T TREK through the lymphoma universe, to boldly go where no other therapy has gone before

G Ghilardi, P Braendstrup, EA Chong… - British Journal of …, 2021 - Wiley Online Library
Chimeric antigen receptor (CAR) T cells (CART) therapies have changed and continue to
change the treatment paradigms for B‐cell malignancies because they can achieve durable …

[HTML][HTML] Exploring the dilemma of allogeneic hematopoietic cell transplantation after chimeric antigen receptor T cell therapy: to transplant or not?

S Bouziana, D Bouzianas - Biology of Blood and Marrow Transplantation, 2020 - Elsevier
Patients with refractory or relapsed (R/R) B cell acute lymphoblastic leukemia (B-ALL) and
highly aggressive B cell non-Hodgkin lymphoma (B-NHL) have a very dismal prognosis and …

[HTML][HTML] Positron emission tomography-imaging assessment for guiding strategy in patients with relapsed/refractory large B-cell lymphoma receiving CAR T cells

J Galtier, L Vercellino, L Chartier, P Olivier… - …, 2023 - ncbi.nlm.nih.gov
The aim of this study was to evaluate the prognostic impact of the F-fluorodeoxyglucose
positron emission tomography response at 1 month (M1) and 3 months (M3) after anti-CD19 …

Biomarkers for prediction of CAR T therapy outcomes: current and future perspectives

L Levstek, L Janžič, A Ihan, AN Kopitar - Frontiers in Immunology, 2024 - frontiersin.org
Chimeric antigen receptor (CAR) T cell therapy holds enormous potential for the treatment of
hematologic malignancies. Despite its benefits, it is still used as a second line of therapy …

Integrative analyses reveal outcome-associated and targetable molecular partnerships between TP53, BRD4, TNFRSF10B, and CDKN1A in diffuse large B-cell …

AL Forberg, J Unrau, KS Weber, AC Rutz, S Lund… - Annals of …, 2024 - Springer
Diffuse large B-cell lymphoma (DLBCL) is a common, genomically heterogenous disease
that presents a clinical challenge despite the success of frontline regimens and second-line …

[PDF][PDF] PET-imaging assessment for guiding strategy in patients with relapsed/refractory large B-cell lymphoma receiving CAR T-cells

J Galtier, L Vercellino, L Chartier, P Olivier… - …, 2022 - scholar.archive.org
The aim of this study was to evaluate the prognostic impact of the FDG-PET response at one
month (M1) and three months (M3) after anti-CD19 CAR T-cells in a multicenter cohort of …