I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

Chronic rhinosinusitis (CRS) is a complex disease consisting of several disease variants
with different underlying pathophysiologies. Limited knowledge of the mechanisms of these …

Objectives: We set out to determine the psychometric validation of a disease‐specific health
related quality of life instrument for use in chronic rhinosinusitis, the 22 item Sinonasal …

The emergence of the severe acute respiratory syndrome coronavirus 2 pandemic has
created an unprecedented healthcare, social, and economic disaster. Wearing of masks and …

Chronic rhinosinusitis (CRS) has been known as a disease with strong infectious and
inflammatory components for decades. The recent advancement in methods identifying …

Background Topical therapies have become an integral component in the management plan
for chronic rhinosinusitis (CRS). Several topical therapy strategies have been evaluated, but …

Objectives/Hypothesis Spontaneous cerebrospinal fluid (CSF) leaks are associated with
increased intracranial pressure (ICP) and considered a manifestation of idiopathic …

It is increasingly recognized that chronic rhinosinusitis (CRS) comprises a spectrum of
different diseases with distinct clinical presentations and pathogenic mechanisms. Defining …