The ability of pathogenic bacteria to affect higher organisms and cause disease is one of the
most dramatic properties of microorganisms. Some pathogens can establish transient …

RcsB, a response regulator of the FixJ/NarL family, is at the center of a complex network of
regulatory inputs and outputs. Cell surface stress is sensed by an outer membrane …

During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors
the expansion of the pathogen population over the microbiota. Here, we show that …

Lack of reproducibility is a prominent problem in biomedical research. An important source
of variation in animal experiments is the microbiome, but little is known about specific …

Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …

Salmonella enterica serovars are associated with an estimated 1 million deaths annually
and are also useful model organisms for investigating the mechanisms of host–bacterium …

Most pathogens are able to infect multiple hosts but some are highly adapted to a single-
host species. A detailed understanding of the basis of host specificity can provide important …

The Salmonella genus comprises a group of pathogens associated with illnesses ranging
from gastroenteritis to typhoid fever. We performed an in silico analysis of comparatively …

Within-host evolution has resulted in thousands of variants of Salmonella that exhibit
remarkable diversity in host range and disease outcome, from broad host range to exquisite …

Highlights•Salmonella enterica is comprised of non-typhoidal and typhoidal
serovars.•Typhoidal Salmonella causes enteric fever instead of self-limiting …