Cancer is still the leading cause of death globally. The approval of the therapeutic use of
monoclonal antibodies against immune checkpoint molecules, notably those that target the …

Medications are a common cause of AKI, especially for patients admitted to hospital wards
and the intensive care unit. Although drug-related kidney injury occurs through different …

Since their introduction into clinical practice a decade ago, immune checkpoint inhibitors
(ICIs) have had an overwhelming impact on cancer treatment. Use of these agents in …

Tertiary lymphoid structures (TLSs) are associated with anti-tumor response following
immune checkpoint inhibitor (ICI) therapy, but a commensurate observation of TLS is absent …

Background In patients receiving immune checkpoint inhibitor (ICI) therapy, acute kidney
injury (AKI) is common, and can occur either from kidney injury unrelated to ICI use or from …

JCI - F18-FDG PET imaging as a diagnostic tool for immune checkpoint inhibitor–associated
acute kidney injury Go to JCI Insight About Editors Consulting Editors For authors Publication …

ABSTRACT Background Immune checkpoint inhibitors (ICIs) have been associated with
acute kidney injury (AKI). However, the occurrence rate of ICI-related AKI has not been …

Introduction Case studies and retrospective chart reviews of health system data have
demonstrated an increased risk of nephrotoxicity in patients receiving immune checkpoint …

Immune checkpoint inhibitors (ICIs) have become a mainstay of cancer therapy, with over 80
FDA‐approved indications. Used in a variety of settings and in combination with each other …

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy and outcomes,
leading to an expanding use in millions of patients worldwide. However, they can cause a …