In Alzheimer's disease (AD), early synaptic dysfunction is associated with the increased
oligomeric amyloid-beta peptide, which causes NMDAR-dependent synaptic depression …

Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

Amyloid-beta (Aß) and hyperphosphorylated tau are hallmark lesions of Alzheimer's disease
(AD). However, the loss of synapses and dysfunctions of neurotransmission are more …

Abstract Calcium (Ca 2+) is a ubiquitous second messenger that regulates various activities
in eukaryotic cells. Especially important role calcium plays in excitable cells. Neurons …

Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …

N-methyl-d-aspartate receptors (NMDARs) play a pivotal role in the synaptic transmission
and synaptic plasticity thought to underlie learning and memory. NMDARs activation has …

Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Alzheimer's disease (AD) is known as the most fatal chronic neurodegenerative disease in
adults along with progressive loss of memory and other cognitive function disorders. Cyclin …