Extracellular vesicles as therapeutic resources in the clinical environment
J Sanz-Ros, C Mas-Bargues, N Romero-García… - International journal of …, 2023 - mdpi.com
The native role of extracellular vesicles (EVs) in mediating the transfer of biomolecules
between cells has raised the possibility to use them as therapeutic vehicles. The …
between cells has raised the possibility to use them as therapeutic vehicles. The …
Engineering strategies for customizing extracellular vesicle uptake in a therapeutic context
A Esmaeili, M Alini, M Baghaban Eslaminejad… - Stem Cell Research & …, 2022 - Springer
Extracellular vesicles (EVs) are advanced therapeutic strategies that can be used to
efficiently treat diseases. Promising features of EVs include their innate therapeutic …
efficiently treat diseases. Promising features of EVs include their innate therapeutic …
Isolation of Aloe saponaria-Derived Extracellular Vesicles and Investigation of Their Potential for Chronic Wound Healing
M Kim, JH Park - Pharmaceutics, 2022 - mdpi.com
A chronic wound is caused by a failure to progress through the normal phases of wound
repair in an orderly and timely manner. To induce skin regeneration while inhibiting chronic …
repair in an orderly and timely manner. To induce skin regeneration while inhibiting chronic …
Endothelial extracellular vesicles: from keepers of health to messengers of disease
A Mathiesen, T Hamilton, N Carter, M Brown… - International Journal of …, 2021 - mdpi.com
Endothelium has a rich vesicular network that allows the exchange of macromolecules
between blood and parenchymal cells. This feature of endothelial cells, along with their …
between blood and parenchymal cells. This feature of endothelial cells, along with their …
Extracellular vesicles and intercellular communication: Challenges for in vivo molecular imaging and tracking
Extracellular vesicles (EVs) are a heterogeneous class of cell-derived membrane vesicles
released by various cell types that serve as mediators of intercellular signaling. When …
released by various cell types that serve as mediators of intercellular signaling. When …
Exploiting the natural properties of extracellular vesicles in targeted delivery towards specific cells and tissues
Extracellular vesicles (EVs) are important mediators of intercellular communication that
participate in many physiological/pathological processes. As such, EVs have unique …
participate in many physiological/pathological processes. As such, EVs have unique …
[HTML][HTML] Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells
L Ottaviani, RP Juni, RC de Abreu, M Sansonetti… - Molecular Therapy, 2022 - cell.com
As mediators of intercellular communication, extracellular vesicles containing molecular
cargo, such as microRNAs, are secreted by cells and taken up by recipient cells to influence …
cargo, such as microRNAs, are secreted by cells and taken up by recipient cells to influence …
Comparative analysis of normoxia-and hypoxia-modified extracellular vesicle therapy in function, perfusion, and collateralization in chronically ischemic myocardium
SA Sabe, CM Xu, BA Potz, A Malhotra, M Sabra… - International Journal of …, 2023 - mdpi.com
We have previously shown that normoxia serum-starved extracellular vesicle (EV) therapy
improves myocardial function, perfusion, and angiogenesis in a swine model of chronic …
improves myocardial function, perfusion, and angiogenesis in a swine model of chronic …
Hypoxia and TNF‐alpha modulate extracellular vesicle release from human induced pluripotent stem cell‐derived cardiomyocytes
M Viola, MP Bebelman, RGC Maas… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as important mediators of intercellular
communication in the heart under homeostatic and pathological conditions, such as …
communication in the heart under homeostatic and pathological conditions, such as …
MicroRNA profile of extracellular vesicles released by Müller glial cells
Introduction As with any other radial glia in the central nervous system, Müller glia derive
from the same neuroepithelial precursors, perform similar functions, and exhibit neurogenic …
from the same neuroepithelial precursors, perform similar functions, and exhibit neurogenic …