Key steps for effective breast cancer prevention
Despite decades of laboratory, epidemiological and clinical research, breast cancer
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …
[HTML][HTML] The translational challenges of precision oncology
The translational challenges in the field of precision oncology are in part related to the
biological complexity and diversity of this disease. Technological advances in genomics …
biological complexity and diversity of this disease. Technological advances in genomics …
[HTML][HTML] The association of depression and all-cause and cause-specific mortality: an umbrella review of systematic reviews and meta-analyses
MO Machado, N Veronese, M Sanches, B Stubbs… - BMC medicine, 2018 - Springer
Background Depression is a prevalent and disabling mental disorder that frequently co-
occurs with a wide range of chronic conditions. Evidence has suggested that depression …
occurs with a wide range of chronic conditions. Evidence has suggested that depression …
Medication use to reduce risk of breast cancer: US preventive services task force recommendation statement
DK Owens, KW Davidson, AH Krist, MJ Barry… - Jama, 2019 - jamanetwork.com
Importance Breast cancer is the most common nonskin cancer among women in the United
States and the second leading cause of cancer death. The median age at diagnosis is 62 …
States and the second leading cause of cancer death. The median age at diagnosis is 62 …
Cost-effectiveness of population-based BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2 mutation testing in unselected general population women
R Manchanda, S Patel, VS Gordeev… - JNCI: Journal of the …, 2018 - academic.oup.com
Background The cost-effectiveness of population-based panel testing for high-and moderate-
penetrance ovarian cancer (OC)/breast cancer (BC) gene mutations is unknown. We …
penetrance ovarian cancer (OC)/breast cancer (BC) gene mutations is unknown. We …
Depression in cancer: the many biobehavioral pathways driving tumor progression
Abstract Major Depressive Disorder (MDD) is common among cancer patients, with
prevalence rates up to four-times higher than the general population. Depression confers …
prevalence rates up to four-times higher than the general population. Depression confers …
Preventing progression from arthralgia to arthritis: targeting the right patients
HW Van Steenbergen, JAP Da Silva… - Nature Reviews …, 2018 - nature.com
Early treatment is associated with improved outcomes in patients with rheumatoid arthritis
(RA), suggesting that a'window of opportunity', in which the disease is most susceptible to …
(RA), suggesting that a'window of opportunity', in which the disease is most susceptible to …
Medication use for the risk reduction of primary breast cancer in women: updated evidence report and systematic review for the US Preventive Services Task Force
Importance Medications to reduce risk of breast cancer are effective for women at increased
risk but also cause adverse effects. Objective To update the 2013 US Preventive Services …
risk but also cause adverse effects. Objective To update the 2013 US Preventive Services …
[HTML][HTML] Economic Evaluation of Population-Based BRCA1/BRCA2 Mutation Testing across Multiple Countries and Health Systems
R Manchanda, L Sun, S Patel, O Evans, J Wilschut… - Cancers, 2020 - mdpi.com
Clinical criteria/Family history-based BRCA testing misses a large proportion of BRCA
carriers who can benefit from screening/prevention. We estimate the cost-effectiveness of …
carriers who can benefit from screening/prevention. We estimate the cost-effectiveness of …
[HTML][HTML] Proactive breast cancer risk assessment in primary care: a review based on the principles of screening
In the UK, the National Institute for Health and Care Excellence (NICE) recommends that
women at moderate or high risk of breast cancer be offered risk-reducing medication and …
women at moderate or high risk of breast cancer be offered risk-reducing medication and …