Recent advances in hepatocellular carcinoma therapy

R Dutta, RI Mahato - Pharmacology & therapeutics, 2017 - Elsevier
Hepatocellular carcinoma (HCC), also called malignant hepatoma, is one of the deadliest
cancers due to its complexities, reoccurrence after surgical resection, metastasis and …

The use of nanotechnology to combat liver cancer: Progress and perspectives

KJ Mintz, RM Leblanc - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Liver cancer is one of the most common cancers worldwide and is also one of the most
difficult cancers to treat, resulting in almost one million deaths per year, and the danger of …

[HTML][HTML] Cancer nanotechnology: Enhancing tumor cell response to chemotherapy for hepatocellular carcinoma therapy

Y Sun, W Ma, Y Yang, M He, A Li, L Bai, B Yu… - Asian journal of …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is one of the deadliest cancers due to its complexities,
reoccurrence after surgical resection, metastasis and heterogeneity. In addition to sorafenib …

[HTML][HTML] Glycyrrhizic acid and its hydrolyzed metabolite 18β-glycyrrhetinic acid as specific ligands for targeting nanosystems in the treatment of liver cancer

LA Stecanella, APR Bitencourt, GR Vaz, E Quarta… - Pharmaceutics, 2021 - mdpi.com
Glycyrrhizic acid and its hydrolyzed metabolite 18β-glycyrrhetinic acid, obtained from the
plant Glycyrrhiza glabra, have numerous pharmacological activities, such as anti …

Glycyrrhetinic acid mediated drug delivery carriers for hepatocellular carcinoma therapy

Y Cai, Y Xu, HF Chan, X Fang, C He… - Molecular …, 2016 - ACS Publications
Glycyrrhetinic acid (GA), the main hydrolysate of glycyrrhizic acid extracted from the root of
licorice, has been used in hepatocellular carcinoma (HCC) therapy. Particularly, GA as a …

Surface receptor‐mediated targeted drug delivery systems for enhanced cancer treatment: A state‐of‐the‐art review

S Kunjiappan, P Pavadai, S Vellaichamy… - Drug Development …, 2021 - Wiley Online Library
Enhanced cancer treatment remains as one of the focused areas for researchers around the
world. Hence, the progress in this direction will be a challenge and an opportunity in, inter …

[HTML][HTML] Recent advances in glycyrrhetinic acid-functionalized biomaterials for liver cancer-targeting therapy

A Speciale, C Muscarà, MS Molonia, M Cristani… - Molecules, 2022 - mdpi.com
Liver cancer is one of the most common causes of cancer mortality worldwide.
Chemotherapy and radiotherapy are the conventional therapies generally employed in …

Nanomedicines for advanced cancer treatments: Transitioning towards responsive systems

M van Elk, BP Murphy, T Eufrásio-da-Silva… - International journal of …, 2016 - Elsevier
The development of nanomedicines for the treatment of cancer focuses on the local targeted
delivery of chemotherapeutic drugs to enhance drug efficacy and reduce adverse effects …

Research progress on the protective effects of licorice-derived 18β-glycyrrhetinic acid against liver injury

S Wu, W Wang, J Dou, L Gong - Acta Pharmacologica Sinica, 2021 - nature.com
The first description of the medical use of licorice appeared in “Shennong Bencao Jing”, one
of the well-known Chinese herbal medicine classic books dated back to 220–280 AD. As …

Surface engineering of nanoparticles for targeted delivery to hepatocellular carcinoma

J Lu, J Wang, D Ling - Small, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer‐associated deaths
worldwide. There is a lack of efficient therapy for HCC; the only available first‐line systemic …